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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DUS2L
All Species:
17.88
Human Site:
T369
Identified Species:
30.26
UniProt:
Q9NX74
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NX74
NP_060273.1
493
55050
T369
R
A
Y
P
A
Q
I
T
P
K
M
C
L
L
E
Chimpanzee
Pan troglodytes
XP_001166638
493
55074
T369
R
A
Y
P
A
Q
I
T
P
K
M
C
L
L
E
Rhesus Macaque
Macaca mulatta
XP_001097732
492
55071
T368
R
A
Y
P
A
Q
I
T
P
K
M
C
L
L
E
Dog
Lupus familis
XP_546866
560
62189
T436
R
A
Y
S
P
Q
I
T
P
K
M
C
L
L
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9D7B1
493
55306
T369
R
A
Y
P
P
Q
I
T
P
K
M
C
L
L
E
Rat
Rattus norvegicus
Q8K582
438
49691
R341
W
I
C
Q
P
Y
I
R
P
G
P
K
E
G
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_414079
518
58426
K396
Y
P
P
Q
I
T
P
K
M
Y
L
L
E
W
C
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001342694
504
56694
K374
Y
P
P
Q
I
T
P
K
M
F
L
L
E
W
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572950
473
52758
I376
I
T
D
E
Y
D
G
I
I
C
R
H
M
P
F
Honey Bee
Apis mellifera
XP_393745
457
52069
V360
K
I
L
E
E
E
D
V
I
L
M
H
C
A
F
Nematode Worm
Caenorhab. elegans
NP_493554
436
48980
Y339
R
V
D
D
D
G
V
Y
N
I
E
V
S
F
P
Sea Urchin
Strong. purpuratus
XP_001190481
278
31026
G181
V
A
A
L
A
V
H
G
R
L
T
E
E
R
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001132459
320
35812
A223
D
F
K
R
I
K
D
A
T
G
A
A
S
V
M
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53720
384
42798
D287
I
Q
W
A
T
K
F
D
N
H
I
G
N
T
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
96.7
80.1
N.A.
90.2
22.5
N.A.
N.A.
67.5
N.A.
60.9
N.A.
44.4
42.5
37.9
38.7
Protein Similarity:
100
99.5
98.5
84.6
N.A.
95.3
39.7
N.A.
N.A.
79.7
N.A.
76.9
N.A.
60.4
59.4
56.5
48
P-Site Identity:
100
100
100
86.6
N.A.
93.3
13.3
N.A.
N.A.
0
N.A.
0
N.A.
0
6.6
6.6
13.3
P-Site Similarity:
100
100
100
86.6
N.A.
93.3
13.3
N.A.
N.A.
6.6
N.A.
6.6
N.A.
6.6
20
13.3
13.3
Percent
Protein Identity:
N.A.
35.5
N.A.
N.A.
30.6
N.A.
Protein Similarity:
N.A.
46.6
N.A.
N.A.
46.6
N.A.
P-Site Identity:
N.A.
0
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
13.3
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
43
8
8
29
0
0
8
0
0
8
8
0
8
0
% A
% Cys:
0
0
8
0
0
0
0
0
0
8
0
36
8
0
8
% C
% Asp:
8
0
15
8
8
8
15
8
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
15
8
8
0
0
0
0
8
8
29
0
36
% E
% Phe:
0
8
0
0
0
0
8
0
0
8
0
0
0
8
15
% F
% Gly:
0
0
0
0
0
8
8
8
0
15
0
8
0
8
0
% G
% His:
0
0
0
0
0
0
8
0
0
8
0
15
0
0
0
% H
% Ile:
15
15
0
0
22
0
43
8
15
8
8
0
0
0
0
% I
% Lys:
8
0
8
0
0
15
0
15
0
36
0
8
0
0
8
% K
% Leu:
0
0
8
8
0
0
0
0
0
15
15
15
36
36
0
% L
% Met:
0
0
0
0
0
0
0
0
15
0
43
0
8
0
8
% M
% Asn:
0
0
0
0
0
0
0
0
15
0
0
0
8
0
0
% N
% Pro:
0
15
15
29
22
0
15
0
43
0
8
0
0
8
15
% P
% Gln:
0
8
0
22
0
36
0
0
0
0
0
0
0
0
0
% Q
% Arg:
43
0
0
8
0
0
0
8
8
0
8
0
0
8
0
% R
% Ser:
0
0
0
8
0
0
0
0
0
0
0
0
15
0
15
% S
% Thr:
0
8
0
0
8
15
0
36
8
0
8
0
0
8
0
% T
% Val:
8
8
0
0
0
8
8
8
0
0
0
8
0
8
0
% V
% Trp:
8
0
8
0
0
0
0
0
0
0
0
0
0
15
0
% W
% Tyr:
15
0
36
0
8
8
0
8
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _