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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DUS2L
All Species:
21.82
Human Site:
T404
Identified Species:
36.92
UniProt:
Q9NX74
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NX74
NP_060273.1
493
55050
T404
R
L
F
S
S
I
V
T
V
A
E
Q
K
Y
Q
Chimpanzee
Pan troglodytes
XP_001166638
493
55074
T404
R
L
F
S
S
I
V
T
V
A
E
Q
K
Y
Q
Rhesus Macaque
Macaca mulatta
XP_001097732
492
55071
T403
R
L
F
S
S
I
V
T
V
A
E
Q
K
Y
Q
Dog
Lupus familis
XP_546866
560
62189
T471
R
L
F
C
S
V
V
T
V
A
E
Q
K
Y
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9D7B1
493
55306
T404
R
M
F
C
S
V
V
T
V
A
E
Q
K
Y
Q
Rat
Rattus norvegicus
Q8K582
438
49691
K372
G
S
M
E
G
L
S
K
N
K
L
K
K
Q
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_414079
518
58426
T429
R
L
F
C
S
V
V
T
V
A
D
Q
K
Y
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001342694
504
56694
I407
R
G
F
Q
S
T
V
I
V
A
D
K
K
Y
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572950
473
52758
G407
Y
V
H
A
V
K
T
G
K
S
P
P
A
Y
E
Honey Bee
Apis mellifera
XP_393745
457
52069
R391
H
K
W
T
Q
T
Q
R
K
K
M
P
N
Y
N
Nematode Worm
Caenorhab. elegans
NP_493554
436
48980
E370
V
L
H
D
Y
C
V
E
T
K
I
P
K
A
T
Sea Urchin
Strong. purpuratus
XP_001190481
278
31026
G212
S
I
P
L
I
T
N
G
G
S
Q
D
I
I
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001132459
320
35812
K254
K
T
P
W
E
D
V
K
R
E
Y
V
R
K
S
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53720
384
42798
E318
F
A
R
C
K
S
P
E
E
V
S
F
V
L
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
96.7
80.1
N.A.
90.2
22.5
N.A.
N.A.
67.5
N.A.
60.9
N.A.
44.4
42.5
37.9
38.7
Protein Similarity:
100
99.5
98.5
84.6
N.A.
95.3
39.7
N.A.
N.A.
79.7
N.A.
76.9
N.A.
60.4
59.4
56.5
48
P-Site Identity:
100
100
100
86.6
N.A.
80
6.6
N.A.
N.A.
73.3
N.A.
53.3
N.A.
6.6
6.6
20
0
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
20
N.A.
N.A.
93.3
N.A.
73.3
N.A.
33.3
20
20
26.6
Percent
Protein Identity:
N.A.
35.5
N.A.
N.A.
30.6
N.A.
Protein Similarity:
N.A.
46.6
N.A.
N.A.
46.6
N.A.
P-Site Identity:
N.A.
6.6
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
20
N.A.
N.A.
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
8
0
0
0
0
0
50
0
0
8
8
0
% A
% Cys:
0
0
0
29
0
8
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
0
8
0
0
0
0
15
8
0
0
0
% D
% Glu:
0
0
0
8
8
0
0
15
8
8
36
0
0
0
8
% E
% Phe:
8
0
50
0
0
0
0
0
0
0
0
8
0
0
0
% F
% Gly:
8
8
0
0
8
0
0
15
8
0
0
0
0
0
0
% G
% His:
8
0
15
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
0
8
22
0
8
0
0
8
0
8
8
0
% I
% Lys:
8
8
0
0
8
8
0
15
15
22
0
15
65
8
15
% K
% Leu:
0
43
0
8
0
8
0
0
0
0
8
0
0
8
8
% L
% Met:
0
8
8
0
0
0
0
0
0
0
8
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
8
0
8
0
0
0
8
0
8
% N
% Pro:
0
0
15
0
0
0
8
0
0
0
8
22
0
0
0
% P
% Gln:
0
0
0
8
8
0
8
0
0
0
8
43
0
8
36
% Q
% Arg:
50
0
8
0
0
0
0
8
8
0
0
0
8
0
15
% R
% Ser:
8
8
0
22
50
8
8
0
0
15
8
0
0
0
8
% S
% Thr:
0
8
0
8
0
22
8
43
8
0
0
0
0
0
8
% T
% Val:
8
8
0
0
8
22
65
0
50
8
0
8
8
0
0
% V
% Trp:
0
0
8
8
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
8
0
0
0
0
0
8
0
0
65
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _