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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DUS2L
All Species:
29.39
Human Site:
Y274
Identified Species:
49.74
UniProt:
Q9NX74
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NX74
NP_060273.1
493
55050
Y274
Y
I
R
Y
A
V
Q
Y
D
N
H
Y
T
N
T
Chimpanzee
Pan troglodytes
XP_001166638
493
55074
Y274
Y
I
R
Y
A
V
Q
Y
D
N
H
Y
T
N
T
Rhesus Macaque
Macaca mulatta
XP_001097732
492
55071
Y273
Y
I
R
Y
A
V
Q
Y
D
N
H
Y
T
N
T
Dog
Lupus familis
XP_546866
560
62189
Y341
Y
I
R
Y
A
V
Q
Y
E
N
H
Y
T
N
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9D7B1
493
55306
Y274
Y
I
R
Y
A
V
Q
Y
D
N
H
Y
T
N
T
Rat
Rattus norvegicus
Q8K582
438
49691
S246
P
A
L
F
E
G
R
S
P
A
V
W
E
L
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_414079
518
58426
Y301
Y
I
K
Y
A
V
R
Y
D
N
H
Y
T
N
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001342694
504
56694
Y279
Y
I
T
Y
A
V
R
Y
D
N
N
P
F
N
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572950
473
52758
R281
E
L
I
E
K
Y
L
R
L
C
V
D
Y
D
N
Honey Bee
Apis mellifera
XP_393745
457
52069
Y265
M
E
D
V
I
K
S
Y
L
K
Y
A
V
D
C
Nematode Worm
Caenorhab. elegans
NP_493554
436
48980
S244
R
K
A
L
S
T
P
S
I
F
R
R
E
G
C
Sea Urchin
Strong. purpuratus
XP_001190481
278
31026
G86
D
R
L
V
F
Q
M
G
T
A
D
A
Q
R
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001132459
320
35812
P128
G
A
A
L
L
S
K
P
E
L
I
H
D
I
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53720
384
42798
T192
L
T
V
H
C
R
K
T
E
M
R
N
R
E
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
96.7
80.1
N.A.
90.2
22.5
N.A.
N.A.
67.5
N.A.
60.9
N.A.
44.4
42.5
37.9
38.7
Protein Similarity:
100
99.5
98.5
84.6
N.A.
95.3
39.7
N.A.
N.A.
79.7
N.A.
76.9
N.A.
60.4
59.4
56.5
48
P-Site Identity:
100
100
100
93.3
N.A.
100
0
N.A.
N.A.
86.6
N.A.
66.6
N.A.
0
6.6
0
0
P-Site Similarity:
100
100
100
100
N.A.
100
20
N.A.
N.A.
100
N.A.
80
N.A.
13.3
20
6.6
0
Percent
Protein Identity:
N.A.
35.5
N.A.
N.A.
30.6
N.A.
Protein Similarity:
N.A.
46.6
N.A.
N.A.
46.6
N.A.
P-Site Identity:
N.A.
0
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
20
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
15
15
0
50
0
0
0
0
15
0
15
0
0
15
% A
% Cys:
0
0
0
0
8
0
0
0
0
8
0
0
0
0
15
% C
% Asp:
8
0
8
0
0
0
0
0
43
0
8
8
8
15
0
% D
% Glu:
8
8
0
8
8
0
0
0
22
0
0
0
15
8
0
% E
% Phe:
0
0
0
8
8
0
0
0
0
8
0
0
8
0
0
% F
% Gly:
8
0
0
0
0
8
0
8
0
0
0
0
0
8
0
% G
% His:
0
0
0
8
0
0
0
0
0
0
43
8
0
0
0
% H
% Ile:
0
50
8
0
8
0
0
0
8
0
8
0
0
8
0
% I
% Lys:
0
8
8
0
8
8
15
0
0
8
0
0
0
0
0
% K
% Leu:
8
8
15
15
8
0
8
0
15
8
0
0
0
8
8
% L
% Met:
8
0
0
0
0
0
8
0
0
8
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
50
8
8
0
50
8
% N
% Pro:
8
0
0
0
0
0
8
8
8
0
0
8
0
0
0
% P
% Gln:
0
0
0
0
0
8
36
0
0
0
0
0
8
0
8
% Q
% Arg:
8
8
36
0
0
8
22
8
0
0
15
8
8
8
0
% R
% Ser:
0
0
0
0
8
8
8
15
0
0
0
0
0
0
0
% S
% Thr:
0
8
8
0
0
8
0
8
8
0
0
0
43
0
50
% T
% Val:
0
0
8
15
0
50
0
0
0
0
15
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% W
% Tyr:
50
0
0
50
0
8
0
58
0
0
8
43
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _