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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DUS2L
All Species:
26.06
Human Site:
Y388
Identified Species:
44.1
UniProt:
Q9NX74
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NX74
NP_060273.1
493
55050
Y388
E
K
L
A
Q
P
V
Y
E
T
V
Q
R
P
L
Chimpanzee
Pan troglodytes
XP_001166638
493
55074
Y388
E
K
L
A
Q
P
V
Y
E
T
V
Q
R
P
L
Rhesus Macaque
Macaca mulatta
XP_001097732
492
55071
Y387
E
K
L
A
Q
P
V
Y
E
T
V
Q
R
P
L
Dog
Lupus familis
XP_546866
560
62189
Y455
E
K
L
A
Q
P
V
Y
D
T
V
Q
R
P
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9D7B1
493
55306
Y388
E
K
L
P
Q
P
V
Y
E
T
V
Q
R
T
I
Rat
Rattus norvegicus
Q8K582
438
49691
S356
K
E
N
S
S
G
R
S
K
R
A
L
E
E
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_414079
518
58426
Y413
E
K
H
P
Q
P
V
Y
E
T
V
Q
R
P
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001342694
504
56694
Y391
E
K
L
E
Q
P
V
Y
E
T
E
Q
R
S
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572950
473
52758
D391
L
R
S
T
Y
P
S
D
N
H
L
P
K
T
Q
Honey Bee
Apis mellifera
XP_393745
457
52069
D375
L
R
N
N
Y
I
T
D
L
E
L
P
K
T
V
Nematode Worm
Caenorhab. elegans
NP_493554
436
48980
V354
L
K
R
L
K
N
S
V
G
F
S
P
T
P
K
Sea Urchin
Strong. purpuratus
XP_001190481
278
31026
A196
R
H
P
V
H
C
D
A
I
K
A
V
A
D
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001132459
320
35812
N238
V
A
R
G
A
M
W
N
A
S
I
F
C
A
K
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53720
384
42798
P302
Y
M
L
S
R
I
V
P
G
K
S
V
F
F
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
96.7
80.1
N.A.
90.2
22.5
N.A.
N.A.
67.5
N.A.
60.9
N.A.
44.4
42.5
37.9
38.7
Protein Similarity:
100
99.5
98.5
84.6
N.A.
95.3
39.7
N.A.
N.A.
79.7
N.A.
76.9
N.A.
60.4
59.4
56.5
48
P-Site Identity:
100
100
100
93.3
N.A.
80
0
N.A.
N.A.
86.6
N.A.
73.3
N.A.
6.6
0
13.3
0
P-Site Similarity:
100
100
100
100
N.A.
86.6
26.6
N.A.
N.A.
86.6
N.A.
73.3
N.A.
26.6
26.6
20
0
Percent
Protein Identity:
N.A.
35.5
N.A.
N.A.
30.6
N.A.
Protein Similarity:
N.A.
46.6
N.A.
N.A.
46.6
N.A.
P-Site Identity:
N.A.
0
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
13.3
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
29
8
0
0
8
8
0
15
0
8
8
0
% A
% Cys:
0
0
0
0
0
8
0
0
0
0
0
0
8
0
0
% C
% Asp:
0
0
0
0
0
0
8
15
8
0
0
0
0
8
0
% D
% Glu:
50
8
0
8
0
0
0
0
43
8
8
0
8
8
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
8
0
8
8
8
0
% F
% Gly:
0
0
0
8
0
8
0
0
15
0
0
0
0
0
0
% G
% His:
0
8
8
0
8
0
0
0
0
8
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
15
0
0
8
0
8
0
0
0
8
% I
% Lys:
8
58
0
0
8
0
0
0
8
15
0
0
15
0
15
% K
% Leu:
22
0
50
8
0
0
0
0
8
0
15
8
0
0
36
% L
% Met:
0
8
0
0
0
8
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
15
8
0
8
0
8
8
0
0
0
0
0
0
% N
% Pro:
0
0
8
15
0
58
0
8
0
0
0
22
0
43
0
% P
% Gln:
0
0
0
0
50
0
0
0
0
0
0
50
0
0
22
% Q
% Arg:
8
15
15
0
8
0
8
0
0
8
0
0
50
0
0
% R
% Ser:
0
0
8
15
8
0
15
8
0
8
15
0
0
8
8
% S
% Thr:
0
0
0
8
0
0
8
0
0
50
0
0
8
22
0
% T
% Val:
8
0
0
8
0
0
58
8
0
0
43
15
0
0
8
% V
% Trp:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
15
0
0
50
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _