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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
OPA1L
All Species:
16.97
Human Site:
S235
Identified Species:
46.67
UniProt:
Q9NX94
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NX94
NP_001077382.1
342
37828
S235
S
E
H
G
A
P
D
S
K
E
K
T
P
G
R
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001113270
342
37747
S235
S
E
H
G
A
P
D
S
K
E
K
T
P
G
R
Dog
Lupus familis
XP_851200
343
37730
S236
Q
G
S
A
L
P
D
S
K
D
K
T
P
G
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8BGW2
348
38329
S241
R
G
G
V
S
P
D
S
E
D
K
T
P
G
R
Rat
Rattus norvegicus
P0C1G7
344
37966
S237
H
G
G
A
P
P
D
S
K
D
K
T
P
G
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511720
516
56039
S410
P
S
G
A
F
P
D
S
K
D
K
T
P
G
R
Chicken
Gallus gallus
XP_421732
343
38090
A236
Q
S
S
A
I
P
D
A
K
D
K
T
P
G
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001018467
334
38350
E229
R
N
M
A
M
P
E
E
K
E
R
I
Q
G
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791639
312
34700
P220
L
S
T
G
T
Q
F
P
E
H
L
Q
Q
Q
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.8
92.7
N.A.
86.4
89.8
N.A.
54.6
72
N.A.
48.8
N.A.
N.A.
N.A.
N.A.
21.9
Protein Similarity:
100
N.A.
99.4
95
N.A.
90.2
93.3
N.A.
57.9
79
N.A.
61.7
N.A.
N.A.
N.A.
N.A.
34.5
P-Site Identity:
100
N.A.
100
60
N.A.
53.3
60
N.A.
60
53.3
N.A.
33.3
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
N.A.
100
66.6
N.A.
73.3
66.6
N.A.
66.6
66.6
N.A.
46.6
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
56
23
0
0
12
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
78
0
0
56
0
0
0
0
0
% D
% Glu:
0
23
0
0
0
0
12
12
23
34
0
0
0
0
0
% E
% Phe:
0
0
0
0
12
0
12
0
0
0
0
0
0
0
0
% F
% Gly:
0
34
34
34
0
0
0
0
0
0
0
0
0
89
0
% G
% His:
12
0
23
0
0
0
0
0
0
12
0
0
0
0
0
% H
% Ile:
0
0
0
0
12
0
0
0
0
0
0
12
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
78
0
78
0
0
0
0
% K
% Leu:
12
0
0
0
12
0
0
0
0
0
12
0
0
0
12
% L
% Met:
0
0
12
0
12
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
12
0
0
0
12
89
0
12
0
0
0
0
78
0
0
% P
% Gln:
23
0
0
0
0
12
0
0
0
0
0
12
23
12
0
% Q
% Arg:
23
0
0
0
0
0
0
0
0
0
12
0
0
0
89
% R
% Ser:
23
34
23
0
12
0
0
67
0
0
0
0
0
0
0
% S
% Thr:
0
0
12
0
12
0
0
0
0
0
0
78
0
0
0
% T
% Val:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _