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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SIRT5
All Species:
11.82
Human Site:
Y16
Identified Species:
23.64
UniProt:
Q9NXA8
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NXA8
NP_036373.1
310
33881
Y16
S
R
L
I
S
Q
L
Y
C
G
L
K
P
P
A
Chimpanzee
Pan troglodytes
XP_001169349
310
33894
Y16
G
R
L
I
S
Q
L
Y
C
G
L
K
P
P
A
Rhesus Macaque
Macaca mulatta
XP_001091987
310
33862
Y16
S
R
L
I
S
Q
L
Y
C
G
L
K
P
P
A
Dog
Lupus familis
XP_535891
310
33924
Y16
C
R
L
L
Y
G
L
Y
R
G
L
K
S
P
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8K2C6
310
34116
C16
G
R
F
I
S
Q
L
C
C
R
R
K
P
P
A
Rat
Rattus norvegicus
Q68FX9
310
34080
C16
G
R
L
F
S
Q
L
C
C
G
P
K
P
S
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514986
396
42939
G102
A
N
L
V
S
R
L
G
G
E
L
K
L
P
A
Chicken
Gallus gallus
XP_418925
423
45358
V129
A
R
R
L
L
A
Q
V
H
G
A
L
K
P
A
Frog
Xenopus laevis
NP_001088966
309
34085
A15
T
R
R
L
V
S
H
A
Y
C
G
L
K
P
A
Zebra Danio
Brachydanio rerio
NP_001002605
305
33910
H15
C
S
R
G
S
T
S
H
L
C
A
A
V
R
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_625080
265
29423
N16
E
I
V
A
N
A
K
N
V
L
I
L
T
G
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780446
226
25512
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.3
98
87
N.A.
86.1
85.4
N.A.
66.1
58.3
76.4
69.3
N.A.
N.A.
50.9
N.A.
44.1
Protein Similarity:
100
98.7
98.7
90.6
N.A.
90
90
N.A.
70.4
64.5
83.2
78.3
N.A.
N.A.
66.7
N.A.
54.1
P-Site Identity:
100
93.3
100
60
N.A.
66.6
66.6
N.A.
46.6
26.6
20
6.6
N.A.
N.A.
0
N.A.
0
P-Site Similarity:
100
93.3
100
66.6
N.A.
66.6
66.6
N.A.
66.6
40
33.3
13.3
N.A.
N.A.
26.6
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
17
0
0
9
0
17
0
9
0
0
17
9
0
0
75
% A
% Cys:
17
0
0
0
0
0
0
17
42
17
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
9
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% E
% Phe:
0
0
9
9
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
25
0
0
9
0
9
0
9
9
50
9
0
0
9
0
% G
% His:
0
0
0
0
0
0
9
9
9
0
0
0
0
0
0
% H
% Ile:
0
9
0
34
0
0
0
0
0
0
9
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
9
0
0
0
0
59
17
0
0
% K
% Leu:
0
0
50
25
9
0
59
0
9
9
42
25
9
0
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
9
0
0
9
0
0
9
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
9
0
42
67
0
% P
% Gln:
0
0
0
0
0
42
9
0
0
0
0
0
0
0
0
% Q
% Arg:
0
67
25
0
0
9
0
0
9
9
9
0
0
9
0
% R
% Ser:
17
9
0
0
59
9
9
0
0
0
0
0
9
9
9
% S
% Thr:
9
0
0
0
0
9
0
0
0
0
0
0
9
0
0
% T
% Val:
0
0
9
9
9
0
0
9
9
0
0
0
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
9
0
0
34
9
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _