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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MKS1
All Species:
18.18
Human Site:
S504
Identified Species:
40
UniProt:
Q9NXB0
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NXB0
NP_060247.2
559
64528
S504
R
A
F
M
E
S
S
S
L
Q
K
R
M
R
S
Chimpanzee
Pan troglodytes
XP_001172592
559
64593
S504
R
A
F
M
E
S
S
S
L
R
K
R
M
R
S
Rhesus Macaque
Macaca mulatta
XP_001103807
582
67318
S527
R
A
F
M
E
S
S
S
L
R
K
R
M
R
S
Dog
Lupus familis
XP_548230
625
71517
F570
R
A
F
M
E
S
S
F
L
R
K
R
M
R
S
Cat
Felis silvestris
Mouse
Mus musculus
Q5SW45
561
64397
S507
R
A
F
M
E
S
N
S
L
Q
K
Q
M
R
S
Rat
Rattus norvegicus
Q499Q5
561
64504
S507
R
A
F
M
E
S
N
S
L
R
K
Q
M
R
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520585
416
47671
P368
G
Y
G
A
V
V
L
P
S
T
P
G
F
H
T
Chicken
Gallus gallus
XP_415705
524
60060
L476
M
Q
S
V
L
D
R
L
G
G
F
S
Q
Q
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572804
699
80065
Q625
R
Q
I
D
T
S
D
Q
F
H
H
H
F
H
L
Honey Bee
Apis mellifera
XP_001120316
448
52853
I400
P
K
G
H
E
D
K
I
L
N
K
S
Q
L
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_787637
523
59905
F475
Y
D
D
M
R
R
F
F
I
G
G
S
P
E
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
91.4
81.7
N.A.
88.9
86.9
N.A.
60.2
67
N.A.
N.A.
N.A.
22.3
26.8
N.A.
42.2
Protein Similarity:
100
99.4
93.1
86.2
N.A.
95
94.4
N.A.
68.1
78.1
N.A.
N.A.
N.A.
36.4
42.4
N.A.
61.1
P-Site Identity:
100
93.3
93.3
86.6
N.A.
86.6
80
N.A.
0
6.6
N.A.
N.A.
N.A.
13.3
20
N.A.
6.6
P-Site Similarity:
100
100
100
93.3
N.A.
100
100
N.A.
6.6
20
N.A.
N.A.
N.A.
13.3
26.6
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
55
0
10
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
10
10
0
19
10
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
64
0
0
0
0
0
0
0
0
10
0
% E
% Phe:
0
0
55
0
0
0
10
19
10
0
10
0
19
0
0
% F
% Gly:
10
0
19
0
0
0
0
0
10
19
10
10
0
0
0
% G
% His:
0
0
0
10
0
0
0
0
0
10
10
10
0
19
0
% H
% Ile:
0
0
10
0
0
0
0
10
10
0
0
0
0
0
0
% I
% Lys:
0
10
0
0
0
0
10
0
0
0
64
0
0
0
0
% K
% Leu:
0
0
0
0
10
0
10
10
64
0
0
0
0
10
19
% L
% Met:
10
0
0
64
0
0
0
0
0
0
0
0
55
0
0
% M
% Asn:
0
0
0
0
0
0
19
0
0
10
0
0
0
0
10
% N
% Pro:
10
0
0
0
0
0
0
10
0
0
10
0
10
0
0
% P
% Gln:
0
19
0
0
0
0
0
10
0
19
0
19
19
10
0
% Q
% Arg:
64
0
0
0
10
10
10
0
0
37
0
37
0
55
0
% R
% Ser:
0
0
10
0
0
64
37
46
10
0
0
28
0
0
64
% S
% Thr:
0
0
0
0
10
0
0
0
0
10
0
0
0
0
10
% T
% Val:
0
0
0
10
10
10
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _