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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MKS1
All Species:
24.85
Human Site:
Y107
Identified Species:
54.67
UniProt:
Q9NXB0
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NXB0
NP_060247.2
559
64528
Y107
Q
S
P
L
D
Y
Q
Y
R
Q
E
I
L
K
L
Chimpanzee
Pan troglodytes
XP_001172592
559
64593
Y107
Q
S
P
L
D
Y
Q
Y
R
Q
E
I
L
K
L
Rhesus Macaque
Macaca mulatta
XP_001103807
582
67318
Y130
Q
S
P
L
D
Y
Q
Y
R
Q
E
I
L
K
L
Dog
Lupus familis
XP_548230
625
71517
Y173
Q
S
P
L
D
H
Q
Y
R
Q
E
I
L
K
L
Cat
Felis silvestris
Mouse
Mus musculus
Q5SW45
561
64397
Y107
Q
S
P
L
D
H
Q
Y
R
Q
E
I
L
K
L
Rat
Rattus norvegicus
Q499Q5
561
64504
Y107
Q
S
P
L
D
H
Q
Y
R
Q
E
V
L
K
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520585
416
47671
Chicken
Gallus gallus
XP_415705
524
60060
H94
R
I
F
T
Y
T
D
H
D
R
F
T
N
L
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572804
699
80065
Y194
A
S
K
L
Q
R
R
Y
H
R
W
A
L
E
T
Honey Bee
Apis mellifera
XP_001120316
448
52853
E18
A
A
T
Y
K
V
K
E
P
I
S
N
F
K
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_787637
523
59905
L93
P
N
T
E
N
E
D
L
Y
I
F
D
W
Q
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
91.4
81.7
N.A.
88.9
86.9
N.A.
60.2
67
N.A.
N.A.
N.A.
22.3
26.8
N.A.
42.2
Protein Similarity:
100
99.4
93.1
86.2
N.A.
95
94.4
N.A.
68.1
78.1
N.A.
N.A.
N.A.
36.4
42.4
N.A.
61.1
P-Site Identity:
100
100
100
93.3
N.A.
93.3
86.6
N.A.
0
0
N.A.
N.A.
N.A.
26.6
6.6
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
0
20
N.A.
N.A.
N.A.
46.6
26.6
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
19
10
0
0
0
0
0
0
0
0
0
10
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
55
0
19
0
10
0
0
10
0
0
0
% D
% Glu:
0
0
0
10
0
10
0
10
0
0
55
0
0
10
19
% E
% Phe:
0
0
10
0
0
0
0
0
0
0
19
0
10
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
28
0
10
10
0
0
0
0
0
0
% H
% Ile:
0
10
0
0
0
0
0
0
0
19
0
46
0
0
10
% I
% Lys:
0
0
10
0
10
0
10
0
0
0
0
0
0
64
0
% K
% Leu:
0
0
0
64
0
0
0
10
0
0
0
0
64
10
55
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
0
0
10
0
0
0
0
0
0
10
10
0
0
% N
% Pro:
10
0
55
0
0
0
0
0
10
0
0
0
0
0
0
% P
% Gln:
55
0
0
0
10
0
55
0
0
55
0
0
0
10
0
% Q
% Arg:
10
0
0
0
0
10
10
0
55
19
0
0
0
0
0
% R
% Ser:
0
64
0
0
0
0
0
0
0
0
10
0
0
0
0
% S
% Thr:
0
0
19
10
0
10
0
0
0
0
0
10
0
0
10
% T
% Val:
0
0
0
0
0
10
0
0
0
0
0
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
10
0
10
0
0
% W
% Tyr:
0
0
0
10
10
28
0
64
10
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _