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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MIOS All Species: 20.3
Human Site: S470 Identified Species: 44.67
UniProt: Q9NXC5 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NXC5 NP_061878.3 875 98584 S470 S L G M V E S S R H N W S G L
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001087340 875 98545 S470 S L G M V E S S R H N W S G L
Dog Lupus familis XP_850521 875 98571 S470 S L G M V E S S R H N W S G L
Cat Felis silvestris
Mouse Mus musculus Q8VE19 875 98305 S470 S L G M V E S S R H N W S G L
Rat Rattus norvegicus NP_001167025 875 98392 S470 S L G M V E S S R H N W S G L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis Q5U5D4 880 98638 F474 S M G T T E S F R H S W T G S
Zebra Danio Brachydanio rerio Q802U2 876 98163 R473 S S G T T E T R R C W S G S D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VQ89 867 98584 S468 T S E A L M A S S R I E S Q V
Honey Bee Apis mellifera XP_001122492 780 88039 F416 L L L C G W R F D K D T N S L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_789007 651 73469 Y287 K R R A S N G Y G M K T E P L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P38164 1038 117617 N539 S S K N L Q N N A Y I R N T W
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 99.5 99.1 N.A. 98 98 N.A. N.A. N.A. 87.9 82.3 N.A. 32.6 39.6 N.A. 31
Protein Similarity: 100 N.A. 99.5 99.6 N.A. 98.8 99.1 N.A. N.A. N.A. 93.8 90.8 N.A. 53.3 58.9 N.A. 45.8
P-Site Identity: 100 N.A. 100 100 N.A. 100 100 N.A. N.A. N.A. 53.3 26.6 N.A. 13.3 13.3 N.A. 6.6
P-Site Similarity: 100 N.A. 100 100 N.A. 100 100 N.A. N.A. N.A. 73.3 33.3 N.A. 40 26.6 N.A. 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 25.5 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 43.9 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 46.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 19 0 0 10 0 10 0 0 0 0 0 0 % A
% Cys: 0 0 0 10 0 0 0 0 0 10 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 10 0 10 0 0 0 10 % D
% Glu: 0 0 10 0 0 64 0 0 0 0 0 10 10 0 0 % E
% Phe: 0 0 0 0 0 0 0 19 0 0 0 0 0 0 0 % F
% Gly: 0 0 64 0 10 0 10 0 10 0 0 0 10 55 0 % G
% His: 0 0 0 0 0 0 0 0 0 55 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 19 0 0 0 0 % I
% Lys: 10 0 10 0 0 0 0 0 0 10 10 0 0 0 0 % K
% Leu: 10 55 10 0 19 0 0 0 0 0 0 0 0 0 64 % L
% Met: 0 10 0 46 0 10 0 0 0 10 0 0 0 0 0 % M
% Asn: 0 0 0 10 0 10 10 10 0 0 46 0 19 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % P
% Gln: 0 0 0 0 0 10 0 0 0 0 0 0 0 10 0 % Q
% Arg: 0 10 10 0 0 0 10 10 64 10 0 10 0 0 0 % R
% Ser: 73 28 0 0 10 0 55 55 10 0 10 10 55 19 10 % S
% Thr: 10 0 0 19 19 0 10 0 0 0 0 19 10 10 0 % T
% Val: 0 0 0 0 46 0 0 0 0 0 0 0 0 0 10 % V
% Trp: 0 0 0 0 0 10 0 0 0 0 10 55 0 0 10 % W
% Tyr: 0 0 0 0 0 0 0 10 0 10 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _