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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMPD4
All Species:
10.61
Human Site:
S207
Identified Species:
23.33
UniProt:
Q9NXE4
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NXE4
NP_060221.2
827
93352
S207
G
S
V
P
P
P
L
S
S
S
P
G
G
T
S
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_543560
827
93189
S207
G
S
V
L
P
P
L
S
S
S
P
G
G
P
S
Cat
Felis silvestris
Mouse
Mus musculus
Q6ZPR5
823
93257
C207
G
S
V
P
P
P
L
C
S
S
P
G
G
S
S
Rat
Rattus norvegicus
NP_001161278
823
93261
C207
G
S
V
P
P
P
L
C
S
S
P
G
G
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509989
509
58534
Chicken
Gallus gallus
XP_415236
827
94779
S207
G
S
V
L
P
P
P
S
S
N
P
G
G
A
I
Frog
Xenopus laevis
Q5XHG1
824
93777
S208
G
N
V
P
P
P
H
S
P
N
T
G
G
T
V
Zebra Danio
Brachydanio rerio
Q6PFJ7
791
89972
F201
G
N
V
P
P
S
P
F
S
D
T
R
G
T
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650124
767
86929
A187
T
V
Y
L
K
L
V
A
E
Y
L
N
N
F
L
Honey Bee
Apis mellifera
XP_623882
744
86631
R172
Y
L
Y
H
F
L
P
R
D
N
S
P
V
L
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784153
874
98584
P193
G
R
A
V
P
P
I
P
V
T
S
S
A
P
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
92
N.A.
89.8
90.3
N.A.
46.1
74.9
66.2
60.5
N.A.
24.2
29.5
N.A.
31
Protein Similarity:
100
N.A.
N.A.
94.5
N.A.
93.8
93.9
N.A.
51.8
83.9
77.6
71.9
N.A.
42.2
47.4
N.A.
49.2
P-Site Identity:
100
N.A.
N.A.
86.6
N.A.
86.6
86.6
N.A.
0
66.6
60
46.6
N.A.
0
0
N.A.
20
P-Site Similarity:
100
N.A.
N.A.
86.6
N.A.
93.3
93.3
N.A.
0
73.3
73.3
53.3
N.A.
13.3
6.6
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
0
0
10
0
0
0
0
10
10
0
% A
% Cys:
0
0
0
0
0
0
0
19
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
10
10
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
10
0
0
10
0
0
0
0
0
10
0
% F
% Gly:
73
0
0
0
0
0
0
0
0
0
0
55
64
0
0
% G
% His:
0
0
0
10
0
0
10
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
10
% I
% Lys:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
10
0
28
0
19
37
0
0
0
10
0
0
10
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
19
0
0
0
0
0
0
0
28
0
10
10
0
0
% N
% Pro:
0
0
0
46
73
64
28
10
10
0
46
10
0
19
10
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
10
0
0
0
0
0
10
0
0
0
10
0
0
0
% R
% Ser:
0
46
0
0
0
10
0
37
55
37
19
10
0
19
37
% S
% Thr:
10
0
0
0
0
0
0
0
0
10
19
0
0
28
10
% T
% Val:
0
10
64
10
0
0
10
0
10
0
0
0
10
0
19
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
19
0
0
0
0
0
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _