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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CCDC49 All Species: 22.73
Human Site: S195 Identified Species: 38.46
UniProt: Q9NXE8 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NXE8 NP_060218.1 425 49647 S195 K H K H R S S S S D R S S S E
Chimpanzee Pan troglodytes XP_511442 425 49656 S195 K H K H R S S S S D R S N S E
Rhesus Macaque Macaca mulatta XP_001084106 361 42039 S154 Q K R M A N S S P V L S K V P
Dog Lupus familis XP_537657 420 49023 S195 K H K H R S S S S D G C S S E
Cat Felis silvestris
Mouse Mus musculus Q9DBF7 416 48793 S195 K H K H R S S S S G G S S S E
Rat Rattus norvegicus NP_001101765 415 48669 S195 K H K H R S S S S D R S S S E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509896 413 46346 R205 A S A S E G E R S R R R V S R
Chicken Gallus gallus Q5ZI03 460 53359 R238 K K K K K K D R K K K K Q Q K
Frog Xenopus laevis NP_001086504 387 45480 S170 I R E M L Q N S L E Q K S K K
Zebra Danio Brachydanio rerio NP_998627 393 46591 K184 K K R K K E K K E K K E K R K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_608705 521 61859 S288 K S K K K K S S D S S D E S S
Honey Bee Apis mellifera XP_624464 265 31449 D67 Q G V I E K K D D K K L D W M
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001201496 510 61353 E220 D S S E S S D E E Q R R D R R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q7SI59 444 51384 H195 R H K H R S H H H R S D R H R
Conservation
Percent
Protein Identity: 100 99.7 83.5 90.3 N.A. 88.9 88.9 N.A. 68.4 20 58.8 54.1 N.A. 33.4 28.4 N.A. 30
Protein Similarity: 100 100 84.2 94.1 N.A. 92.7 93.1 N.A. 77.1 34.3 73.6 70.1 N.A. 53.5 46.1 N.A. 50.7
P-Site Identity: 100 93.3 20 86.6 N.A. 86.6 100 N.A. 20 13.3 13.3 6.6 N.A. 33.3 0 N.A. 13.3
P-Site Similarity: 100 100 40 86.6 N.A. 86.6 100 N.A. 20 33.3 46.6 33.3 N.A. 40 13.3 N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. 29
Protein Similarity: N.A. N.A. N.A. N.A. N.A. 48.2
P-Site Identity: N.A. N.A. N.A. N.A. N.A. 33.3
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. 40
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 8 0 8 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % C
% Asp: 8 0 0 0 0 0 15 8 15 29 0 15 15 0 0 % D
% Glu: 0 0 8 8 15 8 8 8 15 8 0 8 8 0 36 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 8 0 0 0 8 0 0 0 8 15 0 0 0 0 % G
% His: 0 43 0 43 0 0 8 8 8 0 0 0 0 8 0 % H
% Ile: 8 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 58 22 58 22 22 22 15 8 8 22 22 15 15 8 22 % K
% Leu: 0 0 0 0 8 0 0 0 8 0 8 8 0 0 0 % L
% Met: 0 0 0 15 0 0 0 0 0 0 0 0 0 0 8 % M
% Asn: 0 0 0 0 0 8 8 0 0 0 0 0 8 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 8 % P
% Gln: 15 0 0 0 0 8 0 0 0 8 8 0 8 8 0 % Q
% Arg: 8 8 15 0 43 0 0 15 0 15 36 15 8 15 22 % R
% Ser: 0 22 8 8 8 50 50 58 43 8 15 36 36 50 8 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 8 0 0 0 0 0 0 8 0 0 8 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _