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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CCDC49 All Species: 12.12
Human Site: S288 Identified Species: 20.51
UniProt: Q9NXE8 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NXE8 NP_060218.1 425 49647 S288 S R D R R S R S L G R R S R S
Chimpanzee Pan troglodytes XP_511442 425 49656 S288 S R D R R S R S L G R R S R S
Rhesus Macaque Macaca mulatta XP_001084106 361 42039 T247 S K V N R R E T G Q T R S P S
Dog Lupus familis XP_537657 420 49023 S288 S R D P G R R S R S P R P S K
Cat Felis silvestris
Mouse Mus musculus Q9DBF7 416 48793 R288 R S P S R R S R S P R P S K P
Rat Rattus norvegicus NP_001101765 415 48669 S288 S P G R K S L S P R P S K Q H
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509896 413 46346 P298 G L G R G G G P P R T L L T P
Chicken Gallus gallus Q5ZI03 460 53359 R331 H G N K D K D R E K Y R L L K
Frog Xenopus laevis NP_001086504 387 45480 S263 S Q S P H R D S K G S K T G G
Zebra Danio Brachydanio rerio NP_998627 393 46591 A277 S R E S E R K A K P K A P S P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_608705 521 61859 D381 K A R R Q S K D T S K Q R E K
Honey Bee Apis mellifera XP_624464 265 31449 L160 E M E T R N Q L L K N P V K L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001201496 510 61353 Q313 K D E K K M R Q R R D C S D D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q7SI59 444 51384 Q288 S R R H R F P Q G R S R S R S
Conservation
Percent
Protein Identity: 100 99.7 83.5 90.3 N.A. 88.9 88.9 N.A. 68.4 20 58.8 54.1 N.A. 33.4 28.4 N.A. 30
Protein Similarity: 100 100 84.2 94.1 N.A. 92.7 93.1 N.A. 77.1 34.3 73.6 70.1 N.A. 53.5 46.1 N.A. 50.7
P-Site Identity: 100 100 33.3 40 N.A. 20 26.6 N.A. 6.6 6.6 20 13.3 N.A. 13.3 13.3 N.A. 13.3
P-Site Similarity: 100 100 46.6 40 N.A. 26.6 40 N.A. 6.6 20 40 40 N.A. 40 40 N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. 29
Protein Similarity: N.A. N.A. N.A. N.A. N.A. 48.2
P-Site Identity: N.A. N.A. N.A. N.A. N.A. 46.6
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. 46.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 0 0 0 0 8 0 0 0 8 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % C
% Asp: 0 8 22 0 8 0 15 8 0 0 8 0 0 8 8 % D
% Glu: 8 0 22 0 8 0 8 0 8 0 0 0 0 8 0 % E
% Phe: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % F
% Gly: 8 8 15 0 15 8 8 0 15 22 0 0 0 8 8 % G
% His: 8 0 0 8 8 0 0 0 0 0 0 0 0 0 8 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 15 8 0 15 15 8 15 0 15 15 15 8 8 15 22 % K
% Leu: 0 8 0 0 0 0 8 8 22 0 0 8 15 8 8 % L
% Met: 0 8 0 0 0 8 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 8 8 0 8 0 0 0 0 8 0 0 0 0 % N
% Pro: 0 8 8 15 0 0 8 8 15 15 15 15 15 8 22 % P
% Gln: 0 8 0 0 8 0 8 15 0 8 0 8 0 8 0 % Q
% Arg: 8 36 15 36 43 36 29 15 15 29 22 43 8 22 0 % R
% Ser: 58 8 8 15 0 29 8 36 8 15 15 8 43 15 29 % S
% Thr: 0 0 0 8 0 0 0 8 8 0 15 0 8 8 0 % T
% Val: 0 0 8 0 0 0 0 0 0 0 0 0 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _