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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CCDC49
All Species:
9.7
Human Site:
S316
Identified Species:
16.41
UniProt:
Q9NXE8
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.31
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NXE8
NP_060218.1
425
49647
S316
R
E
T
G
Q
T
R
S
P
S
P
K
K
E
V
Chimpanzee
Pan troglodytes
XP_511442
425
49656
S316
R
E
T
G
Q
T
R
S
P
S
P
K
K
E
V
Rhesus Macaque
Macaca mulatta
XP_001084106
361
42039
E275
Y
T
R
K
L
S
A
E
E
L
E
R
K
R
Q
Dog
Lupus familis
XP_537657
420
49023
K316
T
K
S
P
S
P
R
K
E
V
Y
Q
R
R
H
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBF7
416
48793
Q316
S
P
K
K
E
A
Y
Q
R
R
H
A
S
G
Y
Rat
Rattus norvegicus
NP_001101765
415
48669
R316
P
K
K
E
V
Y
Q
R
R
H
A
S
G
Y
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509896
413
46346
S326
K
D
T
D
R
G
K
S
P
P
P
K
K
E
G
Chicken
Gallus gallus
Q5ZI03
460
53359
S359
E
G
E
R
K
S
K
S
R
Y
Q
R
E
T
E
Frog
Xenopus laevis
NP_001086504
387
45480
R291
Q
E
P
Y
R
R
Q
R
P
S
G
Y
T
K
K
Zebra Danio
Brachydanio rerio
NP_998627
393
46591
A305
N
Y
S
K
R
L
S
A
E
E
L
E
K
K
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_608705
521
61859
K409
R
S
R
S
R
S
S
K
G
D
D
K
R
R
I
Honey Bee
Apis mellifera
XP_624464
265
31449
Q188
E
E
K
E
Q
R
R
Q
E
M
I
A
N
A
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001201496
510
61353
R341
E
K
K
R
R
Q
R
R
D
D
S
E
D
E
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SI59
444
51384
G316
S
R
E
R
D
S
G
G
P
S
S
R
R
D
D
Conservation
Percent
Protein Identity:
100
99.7
83.5
90.3
N.A.
88.9
88.9
N.A.
68.4
20
58.8
54.1
N.A.
33.4
28.4
N.A.
30
Protein Similarity:
100
100
84.2
94.1
N.A.
92.7
93.1
N.A.
77.1
34.3
73.6
70.1
N.A.
53.5
46.1
N.A.
50.7
P-Site Identity:
100
100
6.6
6.6
N.A.
0
0
N.A.
46.6
6.6
20
6.6
N.A.
13.3
20
N.A.
13.3
P-Site Similarity:
100
100
20
33.3
N.A.
6.6
13.3
N.A.
73.3
40
46.6
40
N.A.
40
20
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
29
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
48.2
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
8
8
8
0
0
8
15
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
8
8
0
0
0
8
15
8
0
8
8
8
% D
% Glu:
22
29
15
15
8
0
0
8
29
8
8
15
8
29
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
0
15
0
8
8
8
8
0
8
0
8
8
8
% G
% His:
0
0
0
0
0
0
0
0
0
8
8
0
0
0
8
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
8
% I
% Lys:
8
22
29
22
8
0
15
15
0
0
0
29
36
15
8
% K
% Leu:
0
0
0
0
8
8
0
0
0
8
8
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% M
% Asn:
8
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% N
% Pro:
8
8
8
8
0
8
0
0
36
8
22
0
0
0
0
% P
% Gln:
8
0
0
0
22
8
15
15
0
0
8
8
0
0
8
% Q
% Arg:
22
8
15
22
36
15
36
22
22
8
0
22
22
22
15
% R
% Ser:
15
8
15
8
8
29
15
29
0
29
15
8
8
0
0
% S
% Thr:
8
8
22
0
0
15
0
0
0
0
0
0
8
8
15
% T
% Val:
0
0
0
0
8
0
0
0
0
8
0
0
0
0
15
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
8
0
8
0
8
8
0
0
8
8
8
0
8
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _