Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CCDC49 All Species: 10
Human Site: S318 Identified Species: 16.92
UniProt: Q9NXE8 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NXE8 NP_060218.1 425 49647 S318 T G Q T R S P S P K K E V Y Q
Chimpanzee Pan troglodytes XP_511442 425 49656 S318 T G Q T R S P S P K K E V Y Q
Rhesus Macaque Macaca mulatta XP_001084106 361 42039 L277 R K L S A E E L E R K R Q E M
Dog Lupus familis XP_537657 420 49023 V318 S P S P R K E V Y Q R R H A P
Cat Felis silvestris
Mouse Mus musculus Q9DBF7 416 48793 R318 K K E A Y Q R R H A S G Y T R
Rat Rattus norvegicus NP_001101765 415 48669 H318 K E V Y Q R R H A S G Y T R K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509896 413 46346 P328 T D R G K S P P P K K E G Y T
Chicken Gallus gallus Q5ZI03 460 53359 Y361 E R K S K S R Y Q R E T E R K
Frog Xenopus laevis NP_001086504 387 45480 S293 P Y R R Q R P S G Y T K K L S
Zebra Danio Brachydanio rerio NP_998627 393 46591 E307 S K R L S A E E L E K K R R E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_608705 521 61859 D411 R S R S S K G D D K R R I A E
Honey Bee Apis mellifera XP_624464 265 31449 M190 K E Q R R Q E M I A N A T W R
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001201496 510 61353 D343 K R R Q R R D D S E D E R T R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q7SI59 444 51384 S318 E R D S G G P S S R R D D R N
Conservation
Percent
Protein Identity: 100 99.7 83.5 90.3 N.A. 88.9 88.9 N.A. 68.4 20 58.8 54.1 N.A. 33.4 28.4 N.A. 30
Protein Similarity: 100 100 84.2 94.1 N.A. 92.7 93.1 N.A. 77.1 34.3 73.6 70.1 N.A. 53.5 46.1 N.A. 50.7
P-Site Identity: 100 100 6.6 6.6 N.A. 0 0 N.A. 53.3 6.6 13.3 6.6 N.A. 6.6 13.3 N.A. 13.3
P-Site Similarity: 100 100 20 26.6 N.A. 13.3 13.3 N.A. 66.6 46.6 33.3 46.6 N.A. 40 26.6 N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. 29
Protein Similarity: N.A. N.A. N.A. N.A. N.A. 48.2
P-Site Identity: N.A. N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. 40
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 8 8 8 0 0 8 15 0 8 0 15 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 8 0 0 0 8 15 8 0 8 8 8 0 0 % D
% Glu: 15 15 8 0 0 8 29 8 8 15 8 29 8 8 15 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 15 0 8 8 8 8 0 8 0 8 8 8 0 0 % G
% His: 0 0 0 0 0 0 0 8 8 0 0 0 8 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 8 0 0 0 8 0 0 % I
% Lys: 29 22 8 0 15 15 0 0 0 29 36 15 8 0 15 % K
% Leu: 0 0 8 8 0 0 0 8 8 0 0 0 0 8 0 % L
% Met: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 8 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 8 % N
% Pro: 8 8 0 8 0 0 36 8 22 0 0 0 0 0 8 % P
% Gln: 0 0 22 8 15 15 0 0 8 8 0 0 8 0 15 % Q
% Arg: 15 22 36 15 36 22 22 8 0 22 22 22 15 29 22 % R
% Ser: 15 8 8 29 15 29 0 29 15 8 8 0 0 0 8 % S
% Thr: 22 0 0 15 0 0 0 0 0 0 8 8 15 15 8 % T
% Val: 0 0 8 0 0 0 0 8 0 0 0 0 15 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % W
% Tyr: 0 8 0 8 8 0 0 8 8 8 0 8 8 22 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _