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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CCDC49 All Species: 33.33
Human Site: S394 Identified Species: 56.41
UniProt: Q9NXE8 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NXE8 NP_060218.1 425 49647 S394 I H R M K L E S A S T S S L E
Chimpanzee Pan troglodytes XP_511442 425 49656 S394 I H R M K L E S A S T S S L E
Rhesus Macaque Macaca mulatta XP_001084106 361 42039 S330 I H R M K L E S A S T S S L E
Dog Lupus familis XP_537657 420 49023 S389 I H R M K L E S A S T S S L E
Cat Felis silvestris
Mouse Mus musculus Q9DBF7 416 48793 S385 L H R M K L E S A S T S S L E
Rat Rattus norvegicus NP_001101765 415 48669 S384 I H R M K L E S A S T S S L E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509896 413 46346 E383 H E K E D E R E R K L E K L D
Chicken Gallus gallus Q5ZI03 460 53359 T415 E R H R K N E T R S P S T D G
Frog Xenopus laevis NP_001086504 387 45480 S356 I H Q M K L E S A A S S S V E
Zebra Danio Brachydanio rerio NP_998627 393 46591 S362 I H E M K L E S A A T S S L E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_608705 521 61859 I490 N K E V K K A I A N H N S I G
Honey Bee Apis mellifera XP_624464 265 31449 I237 Q L A V A A D I G T V A S R I
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001201496 510 61353 L479 K F L E K M R L P S N S S V E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q7SI59 444 51384 A379 K K L A A M Q A A A T D L D K
Conservation
Percent
Protein Identity: 100 99.7 83.5 90.3 N.A. 88.9 88.9 N.A. 68.4 20 58.8 54.1 N.A. 33.4 28.4 N.A. 30
Protein Similarity: 100 100 84.2 94.1 N.A. 92.7 93.1 N.A. 77.1 34.3 73.6 70.1 N.A. 53.5 46.1 N.A. 50.7
P-Site Identity: 100 100 100 100 N.A. 93.3 100 N.A. 6.6 26.6 73.3 86.6 N.A. 20 6.6 N.A. 33.3
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 20 40 100 93.3 N.A. 46.6 33.3 N.A. 46.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. 29
Protein Similarity: N.A. N.A. N.A. N.A. N.A. 48.2
P-Site Identity: N.A. N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. 46.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 8 15 8 8 8 72 22 0 8 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 8 0 8 0 0 0 0 8 0 15 8 % D
% Glu: 8 8 15 15 0 8 65 8 0 0 0 8 0 0 65 % E
% Phe: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 15 % G
% His: 8 58 8 0 0 0 0 0 0 0 8 0 0 0 0 % H
% Ile: 50 0 0 0 0 0 0 15 0 0 0 0 0 8 8 % I
% Lys: 15 15 8 0 79 8 0 0 0 8 0 0 8 0 8 % K
% Leu: 8 8 15 0 0 58 0 8 0 0 8 0 8 58 0 % L
% Met: 0 0 0 58 0 15 0 0 0 0 0 0 0 0 0 % M
% Asn: 8 0 0 0 0 8 0 0 0 8 8 8 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 8 0 8 0 0 0 0 % P
% Gln: 8 0 8 0 0 0 8 0 0 0 0 0 0 0 0 % Q
% Arg: 0 8 43 8 0 0 15 0 15 0 0 0 0 8 0 % R
% Ser: 0 0 0 0 0 0 0 58 0 58 8 72 79 0 0 % S
% Thr: 0 0 0 0 0 0 0 8 0 8 58 0 8 0 0 % T
% Val: 0 0 0 15 0 0 0 0 0 0 8 0 0 15 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _