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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CCDC49 All Species: 8.79
Human Site: T245 Identified Species: 14.87
UniProt: Q9NXE8 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NXE8 NP_060218.1 425 49647 T245 Q G L Q G P L T A E Q K R G H
Chimpanzee Pan troglodytes XP_511442 425 49656 T245 Q G L Q G P L T A E Q K R G H
Rhesus Macaque Macaca mulatta XP_001084106 361 42039 P204 R S S S Y S P P R H A S K K S
Dog Lupus familis XP_537657 420 49023 M245 Q G V Q S S L M A K Q K G M H
Cat Felis silvestris
Mouse Mus musculus Q9DBF7 416 48793 G245 R G L Q G S L G E Q R A I K N
Rat Rattus norvegicus NP_001101765 415 48669 G245 Q G L Q G S L G E Q R A V K N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509896 413 46346 P255 S S P L G V G P G P R E R S Q
Chicken Gallus gallus Q5ZI03 460 53359 Y288 K A A Q K K M Y S K K R K K G
Frog Xenopus laevis NP_001086504 387 45480 P220 H K Q R K R S P S P Q D R H R
Zebra Danio Brachydanio rerio NP_998627 393 46591 P234 S G Y G L Q L P A H R S T H S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_608705 521 61859 Q338 R Q S R S P E Q R Q R Q R S P
Honey Bee Apis mellifera XP_624464 265 31449 V117 S Q V S R N H V E H E C I P P
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001201496 510 61353 S270 R N F S G S D S D H E R R K D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q7SI59 444 51384 E245 P R R R S D S E E D R S K Q R
Conservation
Percent
Protein Identity: 100 99.7 83.5 90.3 N.A. 88.9 88.9 N.A. 68.4 20 58.8 54.1 N.A. 33.4 28.4 N.A. 30
Protein Similarity: 100 100 84.2 94.1 N.A. 92.7 93.1 N.A. 77.1 34.3 73.6 70.1 N.A. 53.5 46.1 N.A. 50.7
P-Site Identity: 100 100 0 53.3 N.A. 33.3 40 N.A. 13.3 6.6 13.3 20 N.A. 13.3 0 N.A. 13.3
P-Site Similarity: 100 100 13.3 66.6 N.A. 60 60 N.A. 26.6 53.3 26.6 26.6 N.A. 46.6 13.3 N.A. 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. 29
Protein Similarity: N.A. N.A. N.A. N.A. N.A. 48.2
P-Site Identity: N.A. N.A. N.A. N.A. N.A. 0
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 8 0 0 0 0 0 29 0 8 15 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % C
% Asp: 0 0 0 0 0 8 8 0 8 8 0 8 0 0 8 % D
% Glu: 0 0 0 0 0 0 8 8 29 15 15 8 0 0 0 % E
% Phe: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 43 0 8 43 0 8 15 8 0 0 0 8 15 8 % G
% His: 8 0 0 0 0 0 8 0 0 29 0 0 0 15 22 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 15 0 0 % I
% Lys: 8 8 0 0 15 8 0 0 0 15 8 22 22 36 0 % K
% Leu: 0 0 29 8 8 0 43 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 8 8 0 0 0 0 0 8 0 % M
% Asn: 0 8 0 0 0 8 0 0 0 0 0 0 0 0 15 % N
% Pro: 8 0 8 0 0 22 8 29 0 15 0 0 0 8 15 % P
% Gln: 29 15 8 43 0 8 0 8 0 22 29 8 0 8 8 % Q
% Arg: 29 8 8 22 8 8 0 0 15 0 43 15 43 0 15 % R
% Ser: 22 15 15 22 22 36 15 8 15 0 0 22 0 15 15 % S
% Thr: 0 0 0 0 0 0 0 15 0 0 0 0 8 0 0 % T
% Val: 0 0 15 0 0 8 0 8 0 0 0 0 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 8 0 8 0 0 8 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _