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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
THUMPD1
All Species:
10.61
Human Site:
S295
Identified Species:
23.33
UniProt:
Q9NXG2
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NXG2
NP_060206.2
353
39315
S295
K
L
E
S
A
D
K
S
D
Q
N
N
T
A
E
Chimpanzee
Pan troglodytes
XP_510866
439
48532
S381
K
L
E
S
A
D
K
S
D
Q
N
N
T
A
E
Rhesus Macaque
Macaca mulatta
XP_001089980
353
39261
S295
K
L
E
S
A
D
K
S
D
Q
N
N
T
A
E
Dog
Lupus familis
XP_547104
358
40066
P295
G
K
E
A
K
L
E
P
G
D
K
S
N
D
P
Cat
Felis silvestris
Mouse
Mus musculus
Q99J36
350
38866
L294
K
L
E
P
D
S
K
L
S
Q
S
D
P
P
E
Rat
Rattus norvegicus
NP_001009688
353
38898
S295
L
E
P
G
S
K
L
S
Q
N
D
P
P
K
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_424600
308
35155
S251
I
K
N
V
C
C
L
S
V
V
R
D
Y
V
L
Frog
Xenopus laevis
NP_001088169
283
32445
N227
V
D
L
S
K
P
E
N
T
I
I
V
E
I
I
Zebra Danio
Brachydanio rerio
NP_991220
353
39240
N278
P
Q
E
T
P
S
Q
N
T
D
P
Q
E
T
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VZD8
324
36188
F268
N
Y
L
E
C
K
K
F
N
L
A
E
L
A
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_794869
266
30117
L210
I
V
E
L
L
A
P
L
V
L
Q
G
S
S
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
79.7
98.3
87.9
N.A.
83.8
84.1
N.A.
N.A.
62.6
58.6
47.5
N.A.
33.1
N.A.
N.A.
34.2
Protein Similarity:
100
79.7
98.8
90.7
N.A.
88.9
89.5
N.A.
N.A.
73.3
67.1
66.5
N.A.
54.3
N.A.
N.A.
50.9
P-Site Identity:
100
100
100
6.6
N.A.
40
6.6
N.A.
N.A.
6.6
6.6
6.6
N.A.
13.3
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
26.6
N.A.
53.3
20
N.A.
N.A.
13.3
20
26.6
N.A.
20
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
28
10
0
0
0
0
10
0
0
37
0
% A
% Cys:
0
0
0
0
19
10
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
0
10
28
0
0
28
19
10
19
0
10
0
% D
% Glu:
0
10
64
10
0
0
19
0
0
0
0
10
19
0
37
% E
% Phe:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% F
% Gly:
10
0
0
10
0
0
0
0
10
0
0
10
0
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% H
% Ile:
19
0
0
0
0
0
0
0
0
10
10
0
0
10
10
% I
% Lys:
37
19
0
0
19
19
46
0
0
0
10
0
0
10
0
% K
% Leu:
10
37
19
10
10
10
19
19
0
19
0
0
10
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
10
0
0
0
0
19
10
10
28
28
10
0
10
% N
% Pro:
10
0
10
10
10
10
10
10
0
0
10
10
19
10
19
% P
% Gln:
0
10
0
0
0
0
10
0
10
37
10
10
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% R
% Ser:
0
0
0
37
10
19
0
46
10
0
10
10
10
10
0
% S
% Thr:
0
0
0
10
0
0
0
0
19
0
0
0
28
10
0
% T
% Val:
10
10
0
10
0
0
0
0
19
10
0
10
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
0
0
0
0
0
0
0
0
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _