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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
THUMPD1
All Species:
22.42
Human Site:
Y262
Identified Species:
49.33
UniProt:
Q9NXG2
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NXG2
NP_060206.2
353
39315
Y262
D
Y
M
L
F
R
K
Y
N
L
Q
E
V
V
K
Chimpanzee
Pan troglodytes
XP_510866
439
48532
Y348
D
Y
M
L
F
R
K
Y
N
L
Q
E
V
V
K
Rhesus Macaque
Macaca mulatta
XP_001089980
353
39261
Y262
D
Y
M
L
F
R
K
Y
N
L
Q
E
V
V
K
Dog
Lupus familis
XP_547104
358
40066
Y262
D
Y
M
L
F
R
K
Y
N
L
Q
E
V
V
K
Cat
Felis silvestris
Mouse
Mus musculus
Q99J36
350
38866
K261
K
D
Y
V
L
F
R
K
Y
N
L
Q
E
V
V
Rat
Rattus norvegicus
NP_001009688
353
38898
Y262
D
Y
V
L
F
R
K
Y
N
L
Q
E
V
V
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_424600
308
35155
A218
E
E
V
I
K
E
L
A
G
I
V
G
S
L
N
Frog
Xenopus laevis
NP_001088169
283
32445
N194
Q
I
V
Y
K
A
R
N
N
N
H
M
N
R
E
Zebra Danio
Brachydanio rerio
NP_991220
353
39240
Y245
D
Y
M
L
F
R
K
Y
N
L
Q
E
V
A
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VZD8
324
36188
K235
N
S
K
N
V
G
N
K
V
D
L
K
E
A
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_794869
266
30117
L177
E
M
I
F
P
V
F
L
A
A
D
V
P
D
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
79.7
98.3
87.9
N.A.
83.8
84.1
N.A.
N.A.
62.6
58.6
47.5
N.A.
33.1
N.A.
N.A.
34.2
Protein Similarity:
100
79.7
98.8
90.7
N.A.
88.9
89.5
N.A.
N.A.
73.3
67.1
66.5
N.A.
54.3
N.A.
N.A.
50.9
P-Site Identity:
100
100
100
100
N.A.
6.6
93.3
N.A.
N.A.
0
6.6
93.3
N.A.
6.6
N.A.
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
26.6
100
N.A.
N.A.
33.3
26.6
93.3
N.A.
20
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
10
0
10
10
10
0
0
0
19
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
55
10
0
0
0
0
0
0
0
10
10
0
0
10
0
% D
% Glu:
19
10
0
0
0
10
0
0
0
0
0
55
19
0
10
% E
% Phe:
0
0
0
10
55
10
10
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
10
0
0
10
0
0
10
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% H
% Ile:
0
10
10
10
0
0
0
0
0
10
0
0
0
0
0
% I
% Lys:
10
0
10
0
19
0
55
19
0
0
0
10
0
0
64
% K
% Leu:
0
0
0
55
10
0
10
10
0
55
19
0
0
10
0
% L
% Met:
0
10
46
0
0
0
0
0
0
0
0
10
0
0
0
% M
% Asn:
10
0
0
10
0
0
10
10
64
19
0
0
10
0
10
% N
% Pro:
0
0
0
0
10
0
0
0
0
0
0
0
10
0
0
% P
% Gln:
10
0
0
0
0
0
0
0
0
0
55
10
0
0
0
% Q
% Arg:
0
0
0
0
0
55
19
0
0
0
0
0
0
10
0
% R
% Ser:
0
10
0
0
0
0
0
0
0
0
0
0
10
0
10
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
28
10
10
10
0
0
10
0
10
10
55
55
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
55
10
10
0
0
0
55
10
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _