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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TRMT1 All Species: 12.73
Human Site: S416 Identified Species: 21.54
UniProt: Q9NXH9 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.31
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NXH9 NP_001129507.1 659 72234 S416 G R V L E A V S A N P G R F H
Chimpanzee Pan troglodytes XP_512420 659 72216 S416 G R V L E A V S A N P G R F H
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_533897 599 65123 S392 Y T L D Q L S S T I H C S T P
Cat Felis silvestris
Mouse Mus musculus Q3TX08 663 72331 T415 G R V L D A V T T N P G R F H
Rat Rattus norvegicus NP_001013892 440 47625 M254 C Y S K Y G A M A L K S R A C
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis NP_001121226 601 66478 R382 R I L S A L D R N N S K R F K
Zebra Danio Brachydanio rerio XP_685886 672 74495 S458 Q K V L G A V S G N P T R F R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VK89 578 64939 G375 E T T L Q S L G T Q R R I V G
Honey Bee Apis mellifera XP_392637 501 56267 F315 G P L H D Q H F V S D L L C N
Nematode Worm Caenorhab. elegans Q23270 526 58381 L340 H Q I G P I Y L A P I H S K P
Sea Urchin Strong. purpuratus XP_790648 556 62357 K370 F K Y K D R M K G M M T V V S
Poplar Tree Populus trichocarpa XP_002330951 583 64164 K390 T S I L K S V K S M K D R Y P
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LFU5 593 65826 K382 N S I L N G V K S M K D R Y P
Baker's Yeast Sacchar. cerevisiae P15565 570 64034 P382 G T Y H L A G P M Y A G P L H
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 N.A. 74.9 N.A. 82.8 57.9 N.A. N.A. N.A. 56.2 59.5 N.A. 41.2 39.6 35.6 42.4
Protein Similarity: 100 99.8 N.A. 77 N.A. 88 61.9 N.A. N.A. N.A. 68.1 72.6 N.A. 54.9 53.8 49 58.5
P-Site Identity: 100 100 N.A. 6.6 N.A. 80 13.3 N.A. N.A. N.A. 20 60 N.A. 6.6 6.6 6.6 0
P-Site Similarity: 100 100 N.A. 20 N.A. 93.3 13.3 N.A. N.A. N.A. 26.6 66.6 N.A. 26.6 33.3 20 20
Percent
Protein Identity: 34.2 N.A. N.A. 33.6 32.4 N.A.
Protein Similarity: 51.9 N.A. N.A. 51.9 49.7 N.A.
P-Site Identity: 20 N.A. N.A. 20 26.6 N.A.
P-Site Similarity: 53.3 N.A. N.A. 40 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 8 36 8 0 29 0 8 0 0 8 0 % A
% Cys: 8 0 0 0 0 0 0 0 0 0 0 8 0 8 8 % C
% Asp: 0 0 0 8 22 0 8 0 0 0 8 15 0 0 0 % D
% Glu: 8 0 0 0 15 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 8 0 0 0 0 0 0 8 0 0 0 0 0 36 0 % F
% Gly: 36 0 0 8 8 15 8 8 15 0 0 29 0 0 8 % G
% His: 8 0 0 15 0 0 8 0 0 0 8 8 0 0 29 % H
% Ile: 0 8 22 0 0 8 0 0 0 8 8 0 8 0 0 % I
% Lys: 0 15 0 15 8 0 0 22 0 0 22 8 0 8 8 % K
% Leu: 0 0 22 50 8 15 8 8 0 8 0 8 8 8 0 % L
% Met: 0 0 0 0 0 0 8 8 8 22 8 0 0 0 0 % M
% Asn: 8 0 0 0 8 0 0 0 8 36 0 0 0 0 8 % N
% Pro: 0 8 0 0 8 0 0 8 0 8 29 0 8 0 29 % P
% Gln: 8 8 0 0 15 8 0 0 0 8 0 0 0 0 0 % Q
% Arg: 8 22 0 0 0 8 0 8 0 0 8 8 58 0 8 % R
% Ser: 0 15 8 8 0 15 8 29 15 8 8 8 15 0 8 % S
% Thr: 8 22 8 0 0 0 0 8 22 0 0 15 0 8 0 % T
% Val: 0 0 29 0 0 0 43 0 8 0 0 0 8 15 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 8 15 0 8 0 8 0 0 8 0 0 0 15 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _