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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TRMT1 All Species: 16.67
Human Site: S425 Identified Species: 28.21
UniProt: Q9NXH9 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NXH9 NP_001129507.1 659 72234 S425 N P G R F H T S E R I R G V L
Chimpanzee Pan troglodytes XP_512420 659 72216 S425 N P G R F H T S E R I R G V L
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_533897 599 65123 L401 I H C S T P S L L Q L R S A L
Cat Felis silvestris
Mouse Mus musculus Q3TX08 663 72331 S424 N P G R F H T S M R I Q G V L
Rat Rattus norvegicus NP_001013892 440 47625 E263 L K S R A C H E M A L R I V L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis NP_001121226 601 66478 A391 N S K R F K T A E R I Q G V L
Zebra Danio Brachydanio rerio XP_685886 672 74495 S467 N P T R F R T S K R I E G M L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VK89 578 64939 L384 Q R R I V G V L S M V Q E E L
Honey Bee Apis mellifera XP_392637 501 56267 N324 S D L L C N L N E M K L G T L
Nematode Worm Caenorhab. elegans Q23270 526 58381 V349 P I H S K P F V T S L L E R L
Sea Urchin Strong. purpuratus XP_790648 556 62357 E379 M M T V V S E E L S D C P L Y
Poplar Tree Populus trichocarpa XP_002330951 583 64164 Y399 M K D R Y P A Y D R I S A V L
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LFU5 593 65826 Y391 M K D R Y P A Y D R I C A V L
Baker's Yeast Sacchar. cerevisiae P15565 570 64034 K391 Y A G P L H N K E F I E E V L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 N.A. 74.9 N.A. 82.8 57.9 N.A. N.A. N.A. 56.2 59.5 N.A. 41.2 39.6 35.6 42.4
Protein Similarity: 100 99.8 N.A. 77 N.A. 88 61.9 N.A. N.A. N.A. 68.1 72.6 N.A. 54.9 53.8 49 58.5
P-Site Identity: 100 100 N.A. 13.3 N.A. 86.6 26.6 N.A. N.A. N.A. 66.6 66.6 N.A. 6.6 20 6.6 0
P-Site Similarity: 100 100 N.A. 33.3 N.A. 93.3 33.3 N.A. N.A. N.A. 80 80 N.A. 20 40 13.3 6.6
Percent
Protein Identity: 34.2 N.A. N.A. 33.6 32.4 N.A.
Protein Similarity: 51.9 N.A. N.A. 51.9 49.7 N.A.
P-Site Identity: 33.3 N.A. N.A. 33.3 40 N.A.
P-Site Similarity: 46.6 N.A. N.A. 46.6 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 0 8 0 15 8 0 8 0 0 15 8 0 % A
% Cys: 0 0 8 0 8 8 0 0 0 0 0 15 0 0 0 % C
% Asp: 0 8 15 0 0 0 0 0 15 0 8 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 8 15 36 0 0 15 22 8 0 % E
% Phe: 0 0 0 0 36 0 8 0 0 8 0 0 0 0 0 % F
% Gly: 0 0 29 0 0 8 0 0 0 0 0 0 43 0 0 % G
% His: 0 8 8 0 0 29 8 0 0 0 0 0 0 0 0 % H
% Ile: 8 8 0 8 0 0 0 0 0 0 58 0 8 0 0 % I
% Lys: 0 22 8 0 8 8 0 8 8 0 8 0 0 0 0 % K
% Leu: 8 0 8 8 8 0 8 15 15 0 22 15 0 8 93 % L
% Met: 22 8 0 0 0 0 0 0 15 15 0 0 0 8 0 % M
% Asn: 36 0 0 0 0 8 8 8 0 0 0 0 0 0 0 % N
% Pro: 8 29 0 8 0 29 0 0 0 0 0 0 8 0 0 % P
% Gln: 8 0 0 0 0 0 0 0 0 8 0 22 0 0 0 % Q
% Arg: 0 8 8 58 0 8 0 0 0 50 0 29 0 8 0 % R
% Ser: 8 8 8 15 0 8 8 29 8 15 0 8 8 0 0 % S
% Thr: 0 0 15 0 8 0 36 0 8 0 0 0 0 8 0 % T
% Val: 0 0 0 8 15 0 8 8 0 0 8 0 0 58 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 0 0 0 15 0 0 15 0 0 0 0 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _