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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TRMT1 All Species: 17.88
Human Site: S453 Identified Species: 30.26
UniProt: Q9NXH9 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NXH9 NP_001129507.1 659 72234 S453 Y T L D Q L S S T I H C N T P
Chimpanzee Pan troglodytes XP_512420 659 72216 S453 Y T L D Q L S S T I H C N T P
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_533897 599 65123 A429 K N A V K T D A P S S A L W D
Cat Felis silvestris
Mouse Mus musculus Q3TX08 663 72331 S452 Y T L D Q L S S T I H C N T P
Rat Rattus norvegicus NP_001013892 440 47625 S291 I V P L L S I S A D F Y V R V
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis NP_001121226 601 66478 S419 Y T L D N L S S V I R C N T P
Zebra Danio Brachydanio rerio XP_685886 672 74495 S495 Y T L D H L S S T V H R S T P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VK89 578 64939 V412 C V L K L E I V P M L K F R S
Honey Bee Apis mellifera XP_392637 501 56267 T352 L D I P L Y Y T L N R L M S I
Nematode Worm Caenorhab. elegans Q23270 526 58381 M377 R L Q G V L T M V N E E L D D
Sea Urchin Strong. purpuratus XP_790648 556 62357 R407 C P S Q E K V R S A I L N A G
Poplar Tree Populus trichocarpa XP_002330951 583 64164 A427 L S L H N L C A T L K C T S P
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LFU5 593 65826 A419 L S L H S L S A T L K C T S P
Baker's Yeast Sacchar. cerevisiae P15565 570 64034 E419 Y G T R K R I E G M L S L A K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 N.A. 74.9 N.A. 82.8 57.9 N.A. N.A. N.A. 56.2 59.5 N.A. 41.2 39.6 35.6 42.4
Protein Similarity: 100 99.8 N.A. 77 N.A. 88 61.9 N.A. N.A. N.A. 68.1 72.6 N.A. 54.9 53.8 49 58.5
P-Site Identity: 100 100 N.A. 0 N.A. 100 6.6 N.A. N.A. N.A. 80 73.3 N.A. 6.6 0 6.6 6.6
P-Site Similarity: 100 100 N.A. 13.3 N.A. 100 6.6 N.A. N.A. N.A. 80 86.6 N.A. 13.3 20 13.3 20
Percent
Protein Identity: 34.2 N.A. N.A. 33.6 32.4 N.A.
Protein Similarity: 51.9 N.A. N.A. 51.9 49.7 N.A.
P-Site Identity: 33.3 N.A. N.A. 40 6.6 N.A.
P-Site Similarity: 60 N.A. N.A. 66.6 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 0 0 0 0 22 8 8 0 8 0 15 0 % A
% Cys: 15 0 0 0 0 0 8 0 0 0 0 43 0 0 0 % C
% Asp: 0 8 0 36 0 0 8 0 0 8 0 0 0 8 15 % D
% Glu: 0 0 0 0 8 8 0 8 0 0 8 8 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 8 0 8 0 0 % F
% Gly: 0 8 0 8 0 0 0 0 8 0 0 0 0 0 8 % G
% His: 0 0 0 15 8 0 0 0 0 0 29 0 0 0 0 % H
% Ile: 8 0 8 0 0 0 22 0 0 29 8 0 0 0 8 % I
% Lys: 8 0 0 8 15 8 0 0 0 0 15 8 0 0 8 % K
% Leu: 22 8 58 8 22 58 0 0 8 15 15 15 22 0 0 % L
% Met: 0 0 0 0 0 0 0 8 0 15 0 0 8 0 0 % M
% Asn: 0 8 0 0 15 0 0 0 0 15 0 0 36 0 0 % N
% Pro: 0 8 8 8 0 0 0 0 15 0 0 0 0 0 50 % P
% Gln: 0 0 8 8 22 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 8 0 0 8 0 8 0 8 0 0 15 8 0 15 0 % R
% Ser: 0 15 8 0 8 8 43 43 8 8 8 8 8 22 8 % S
% Thr: 0 36 8 0 0 8 8 8 43 0 0 0 15 36 0 % T
% Val: 0 15 0 8 8 0 8 8 15 8 0 0 8 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % W
% Tyr: 43 0 0 0 0 8 8 0 0 0 0 8 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _