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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TRMT1 All Species: 15.45
Human Site: S461 Identified Species: 26.15
UniProt: Q9NXH9 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NXH9 NP_001129507.1 659 72234 S461 T I H C N T P S L L Q L R S A
Chimpanzee Pan troglodytes XP_512420 659 72216 S461 T I H C N T P S L L Q L R S A
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_533897 599 65123 I437 P S S A L W D I M R C W E K E
Cat Felis silvestris
Mouse Mus musculus Q3TX08 663 72331 R460 T I H C N T P R L L Q L R S A
Rat Rattus norvegicus NP_001013892 440 47625 F299 A D F Y V R V F V R V F T G Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis NP_001121226 601 66478 S427 V I R C N T P S L L Q F R S A
Zebra Danio Brachydanio rerio XP_685886 672 74495 P503 T V H R S T P P M M Q F R S A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VK89 578 64939 A420 P M L K F R S A I L H A G Y R
Honey Bee Apis mellifera XP_392637 501 56267 I360 L N R L M S I I R C I T P S T
Nematode Worm Caenorhab. elegans Q23270 526 58381 V385 V N E E L D D V L Y Y E H N Q
Sea Urchin Strong. purpuratus XP_790648 556 62357 Y415 S A I L N A G Y R V S I S H A
Poplar Tree Populus trichocarpa XP_002330951 583 64164 S435 T L K C T S P S A V I F R S A
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LFU5 593 65826 S427 T L K C T S P S A A L F R S A
Baker's Yeast Sacchar. cerevisiae P15565 570 64034 N427 G M L S L A K N E L S D S P F
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 N.A. 74.9 N.A. 82.8 57.9 N.A. N.A. N.A. 56.2 59.5 N.A. 41.2 39.6 35.6 42.4
Protein Similarity: 100 99.8 N.A. 77 N.A. 88 61.9 N.A. N.A. N.A. 68.1 72.6 N.A. 54.9 53.8 49 58.5
P-Site Identity: 100 100 N.A. 0 N.A. 93.3 0 N.A. N.A. N.A. 80 53.3 N.A. 6.6 6.6 6.6 13.3
P-Site Similarity: 100 100 N.A. 6.6 N.A. 93.3 6.6 N.A. N.A. N.A. 80 80 N.A. 26.6 13.3 13.3 33.3
Percent
Protein Identity: 34.2 N.A. N.A. 33.6 32.4 N.A.
Protein Similarity: 51.9 N.A. N.A. 51.9 49.7 N.A.
P-Site Identity: 46.6 N.A. N.A. 46.6 6.6 N.A.
P-Site Similarity: 66.6 N.A. N.A. 60 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 0 8 0 15 0 8 15 8 0 8 0 0 58 % A
% Cys: 0 0 0 43 0 0 0 0 0 8 8 0 0 0 0 % C
% Asp: 0 8 0 0 0 8 15 0 0 0 0 8 0 0 0 % D
% Glu: 0 0 8 8 0 0 0 0 8 0 0 8 8 0 8 % E
% Phe: 0 0 8 0 8 0 0 8 0 0 0 36 0 0 8 % F
% Gly: 8 0 0 0 0 0 8 0 0 0 0 0 8 8 0 % G
% His: 0 0 29 0 0 0 0 0 0 0 8 0 8 8 0 % H
% Ile: 0 29 8 0 0 0 8 15 8 0 15 8 0 0 0 % I
% Lys: 0 0 15 8 0 0 8 0 0 0 0 0 0 8 0 % K
% Leu: 8 15 15 15 22 0 0 0 36 43 8 22 0 0 0 % L
% Met: 0 15 0 0 8 0 0 0 15 8 0 0 0 0 0 % M
% Asn: 0 15 0 0 36 0 0 8 0 0 0 0 0 8 0 % N
% Pro: 15 0 0 0 0 0 50 8 0 0 0 0 8 8 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 36 0 0 0 15 % Q
% Arg: 0 0 15 8 0 15 0 8 15 15 0 0 50 0 8 % R
% Ser: 8 8 8 8 8 22 8 36 0 0 15 0 15 58 0 % S
% Thr: 43 0 0 0 15 36 0 0 0 0 0 8 8 0 8 % T
% Val: 15 8 0 0 8 0 8 8 8 15 8 0 0 0 0 % V
% Trp: 0 0 0 0 0 8 0 0 0 0 0 8 0 0 0 % W
% Tyr: 0 0 0 8 0 0 0 8 0 8 8 0 0 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _