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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TRMT1 All Species: 8.48
Human Site: S493 Identified Species: 14.36
UniProt: Q9NXH9 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NXH9 NP_001129507.1 659 72234 S493 V K T D A P A S A L W D I M R
Chimpanzee Pan troglodytes XP_512420 659 72216 S493 V K T D A P A S A L W D I M R
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_533897 599 65123 Q469 L S V E P R L Q A N F T I R D
Cat Felis silvestris
Mouse Mus musculus Q3TX08 663 72331 E492 V K T D A P P E A L W D I M R
Rat Rattus norvegicus NP_001013892 440 47625 Q331 G C G A F Y L Q R L G K A S G
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis NP_001121226 601 66478 S459 L K T D A P P S V I W D I M R
Zebra Danio Brachydanio rerio XP_685886 672 74495 G535 V K T D A P A G V L W D I M R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VK89 578 64939 R452 A V L W D I L R S W S K R H P
Honey Bee Apis mellifera XP_392637 501 56267 K392 H A C K T S I K T D A P N E V
Nematode Worm Caenorhab. elegans Q23270 526 58381 K417 A I L N A G F K V S G S H C N
Sea Urchin Strong. purpuratus XP_790648 556 62357 H447 I R A W V K D H P V S E K R L
Poplar Tree Populus trichocarpa XP_002330951 583 64164 D467 L K S D A P M D V I W D I M R
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LFU5 593 65826 E459 I K T D A P M E I I W D I M R
Baker's Yeast Sacchar. cerevisiae P15565 570 64034 L459 L K K V V A G L G S L G F E C
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 N.A. 74.9 N.A. 82.8 57.9 N.A. N.A. N.A. 56.2 59.5 N.A. 41.2 39.6 35.6 42.4
Protein Similarity: 100 99.8 N.A. 77 N.A. 88 61.9 N.A. N.A. N.A. 68.1 72.6 N.A. 54.9 53.8 49 58.5
P-Site Identity: 100 100 N.A. 13.3 N.A. 86.6 6.6 N.A. N.A. N.A. 73.3 86.6 N.A. 0 0 6.6 0
P-Site Similarity: 100 100 N.A. 33.3 N.A. 86.6 6.6 N.A. N.A. N.A. 86.6 86.6 N.A. 6.6 0 13.3 26.6
Percent
Protein Identity: 34.2 N.A. N.A. 33.6 32.4 N.A.
Protein Similarity: 51.9 N.A. N.A. 51.9 49.7 N.A.
P-Site Identity: 60 N.A. N.A. 66.6 6.6 N.A.
P-Site Similarity: 80 N.A. N.A. 80 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 15 8 8 8 58 8 22 0 29 0 8 0 8 0 0 % A
% Cys: 0 8 8 0 0 0 0 0 0 0 0 0 0 8 8 % C
% Asp: 0 0 0 50 8 0 8 8 0 8 0 50 0 0 8 % D
% Glu: 0 0 0 8 0 0 0 15 0 0 0 8 0 15 0 % E
% Phe: 0 0 0 0 8 0 8 0 0 0 8 0 8 0 0 % F
% Gly: 8 0 8 0 0 8 8 8 8 0 15 8 0 0 8 % G
% His: 8 0 0 0 0 0 0 8 0 0 0 0 8 8 0 % H
% Ile: 15 8 0 0 0 8 8 0 8 22 0 0 58 0 0 % I
% Lys: 0 58 8 8 0 8 0 15 0 0 0 15 8 0 0 % K
% Leu: 29 0 15 0 0 0 22 8 0 36 8 0 0 0 8 % L
% Met: 0 0 0 0 0 0 15 0 0 0 0 0 0 50 0 % M
% Asn: 0 0 0 8 0 0 0 0 0 8 0 0 8 0 8 % N
% Pro: 0 0 0 0 8 50 15 0 8 0 0 8 0 0 8 % P
% Gln: 0 0 0 0 0 0 0 15 0 0 0 0 0 0 0 % Q
% Arg: 0 8 0 0 0 8 0 8 8 0 0 0 8 15 50 % R
% Ser: 0 8 8 0 0 8 0 22 8 15 15 8 0 8 0 % S
% Thr: 0 0 43 0 8 0 0 0 8 0 0 8 0 0 0 % T
% Val: 29 8 8 8 15 0 0 0 29 8 0 0 0 0 8 % V
% Trp: 0 0 0 15 0 0 0 0 0 8 50 0 0 0 0 % W
% Tyr: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _