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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TRMT1 All Species: 10.61
Human Site: T381 Identified Species: 17.95
UniProt: Q9NXH9 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NXH9 NP_001129507.1 659 72234 T381 A A C G P P V T P E C E H C G
Chimpanzee Pan troglodytes XP_512420 659 72216 T381 A A C G P P V T P E C E H C G
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_533897 599 65123 T372 R V F V R V F T G Q A K E L P
Cat Felis silvestris
Mouse Mus musculus Q3TX08 663 72331 T380 A A C G P P V T P E C E H C G
Rat Rattus norvegicus NP_001013892 440 47625 L239 T C T D M A V L A G N S G E T
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis NP_001121226 601 66478 S366 G G P I W A E S L H D K D F V
Zebra Danio Brachydanio rerio XP_685886 672 74495 G423 A A T G P P V G P N C E H C G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VK89 578 64939 Q360 I H N P E F V Q D L L T A V Q
Honey Bee Apis mellifera XP_392637 501 56267 H300 K I C N Y K H H E G G P I W L
Nematode Worm Caenorhab. elegans Q23270 526 58381 C325 I S G P G N R C I H C L L P L
Sea Urchin Strong. purpuratus XP_790648 556 62357 H355 F V K R L I T H I D T Y P D R
Poplar Tree Populus trichocarpa XP_002330951 583 64164 W372 Y N M G G P I W S A P I H D Q
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LFU5 593 65826 W364 Y N M G G P I W S A P I H D Q
Baker's Yeast Sacchar. cerevisiae P15565 570 64034 D367 V A Q G P P V D T K C K F C E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 N.A. 74.9 N.A. 82.8 57.9 N.A. N.A. N.A. 56.2 59.5 N.A. 41.2 39.6 35.6 42.4
Protein Similarity: 100 99.8 N.A. 77 N.A. 88 61.9 N.A. N.A. N.A. 68.1 72.6 N.A. 54.9 53.8 49 58.5
P-Site Identity: 100 100 N.A. 6.6 N.A. 100 6.6 N.A. N.A. N.A. 0 80 N.A. 6.6 6.6 6.6 0
P-Site Similarity: 100 100 N.A. 20 N.A. 100 6.6 N.A. N.A. N.A. 13.3 80 N.A. 6.6 6.6 13.3 6.6
Percent
Protein Identity: 34.2 N.A. N.A. 33.6 32.4 N.A.
Protein Similarity: 51.9 N.A. N.A. 51.9 49.7 N.A.
P-Site Identity: 20 N.A. N.A. 20 46.6 N.A.
P-Site Similarity: 26.6 N.A. N.A. 26.6 60 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 29 36 0 0 0 15 0 0 8 15 8 0 8 0 0 % A
% Cys: 0 8 29 0 0 0 0 8 0 0 43 0 0 36 0 % C
% Asp: 0 0 0 8 0 0 0 8 8 8 8 0 8 22 0 % D
% Glu: 0 0 0 0 8 0 8 0 8 22 0 29 8 8 8 % E
% Phe: 8 0 8 0 0 8 8 0 0 0 0 0 8 8 0 % F
% Gly: 8 8 8 50 22 0 0 8 8 15 8 0 8 0 29 % G
% His: 0 8 0 0 0 0 8 15 0 15 0 0 43 0 0 % H
% Ile: 15 8 0 8 0 8 15 0 15 0 0 15 8 0 0 % I
% Lys: 8 0 8 0 0 8 0 0 0 8 0 22 0 0 0 % K
% Leu: 0 0 0 0 8 0 0 8 8 8 8 8 8 8 15 % L
% Met: 0 0 15 0 8 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 15 8 8 0 8 0 0 0 8 8 0 0 0 0 % N
% Pro: 0 0 8 15 36 50 0 0 29 0 15 8 8 8 8 % P
% Gln: 0 0 8 0 0 0 0 8 0 8 0 0 0 0 22 % Q
% Arg: 8 0 0 8 8 0 8 0 0 0 0 0 0 0 8 % R
% Ser: 0 8 0 0 0 0 0 8 15 0 0 8 0 0 0 % S
% Thr: 8 0 15 0 0 0 8 29 8 0 8 8 0 0 8 % T
% Val: 8 15 0 8 0 8 50 0 0 0 0 0 0 8 8 % V
% Trp: 0 0 0 0 8 0 0 15 0 0 0 0 0 8 0 % W
% Tyr: 15 0 0 0 8 0 0 0 0 0 0 8 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _