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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TRMT1 All Species: 20.61
Human Site: T488 Identified Species: 34.87
UniProt: Q9NXH9 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NXH9 NP_001129507.1 659 72234 T488 A C K N A V K T D A P A S A L
Chimpanzee Pan troglodytes XP_512420 659 72216 T488 A C K N A V K T D A P A S A L
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_533897 599 65123 V464 P A F R I L S V E P R L Q A N
Cat Felis silvestris
Mouse Mus musculus Q3TX08 663 72331 T487 A C K N A V K T D A P P E A L
Rat Rattus norvegicus NP_001013892 440 47625 G326 V F Q C V G C G A F Y L Q R L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis NP_001121226 601 66478 T454 A C K N A L K T D A P P S V I
Zebra Danio Brachydanio rerio XP_685886 672 74495 T530 A C K N A V K T D A P A G V L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VK89 578 64939 L447 T N A P P A V L W D I L R S W
Honey Bee Apis mellifera XP_392637 501 56267 C387 N V S Y S H A C K T S I K T D
Nematode Worm Caenorhab. elegans Q23270 526 58381 L412 Q S V R S A I L N A G F K V S
Sea Urchin Strong. purpuratus XP_790648 556 62357 A442 V I W D I I R A W V K D H P V
Poplar Tree Populus trichocarpa XP_002330951 583 64164 S462 V N P L G L K S D A P M D V I
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LFU5 593 65826 T454 V N P L G I K T D A P M E I I
Baker's Yeast Sacchar. cerevisiae P15565 570 64034 K454 L Q V P P L K K V V A G L G S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 N.A. 74.9 N.A. 82.8 57.9 N.A. N.A. N.A. 56.2 59.5 N.A. 41.2 39.6 35.6 42.4
Protein Similarity: 100 99.8 N.A. 77 N.A. 88 61.9 N.A. N.A. N.A. 68.1 72.6 N.A. 54.9 53.8 49 58.5
P-Site Identity: 100 100 N.A. 6.6 N.A. 86.6 6.6 N.A. N.A. N.A. 73.3 86.6 N.A. 0 0 6.6 0
P-Site Similarity: 100 100 N.A. 20 N.A. 86.6 13.3 N.A. N.A. N.A. 86.6 86.6 N.A. 6.6 6.6 20 26.6
Percent
Protein Identity: 34.2 N.A. N.A. 33.6 32.4 N.A.
Protein Similarity: 51.9 N.A. N.A. 51.9 49.7 N.A.
P-Site Identity: 26.6 N.A. N.A. 33.3 6.6 N.A.
P-Site Similarity: 46.6 N.A. N.A. 46.6 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 36 8 8 0 36 15 8 8 8 58 8 22 0 29 0 % A
% Cys: 0 36 0 8 0 0 8 8 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 8 0 0 0 0 50 8 0 8 8 0 8 % D
% Glu: 0 0 0 0 0 0 0 0 8 0 0 0 15 0 0 % E
% Phe: 0 8 8 0 0 0 0 0 0 8 0 8 0 0 0 % F
% Gly: 0 0 0 0 15 8 0 8 0 0 8 8 8 8 0 % G
% His: 0 0 0 0 0 8 0 0 0 0 0 0 8 0 0 % H
% Ile: 0 8 0 0 15 15 8 0 0 0 8 8 0 8 22 % I
% Lys: 0 0 36 0 0 0 58 8 8 0 8 0 15 0 0 % K
% Leu: 8 0 0 15 0 29 0 15 0 0 0 22 8 0 36 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 15 0 0 0 % M
% Asn: 8 22 0 36 0 0 0 0 8 0 0 0 0 0 8 % N
% Pro: 8 0 15 15 15 0 0 0 0 8 50 15 0 8 0 % P
% Gln: 8 8 8 0 0 0 0 0 0 0 0 0 15 0 0 % Q
% Arg: 0 0 0 15 0 0 8 0 0 0 8 0 8 8 0 % R
% Ser: 0 8 8 0 15 0 8 8 0 0 8 0 22 8 15 % S
% Thr: 8 0 0 0 0 0 0 43 0 8 0 0 0 8 0 % T
% Val: 29 8 15 0 8 29 8 8 8 15 0 0 0 29 8 % V
% Trp: 0 0 8 0 0 0 0 0 15 0 0 0 0 0 8 % W
% Tyr: 0 0 0 8 0 0 0 0 0 0 8 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _