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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TRMT1 All Species: 15.76
Human Site: Y74 Identified Species: 26.67
UniProt: Q9NXH9 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.31
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NXH9 NP_001129507.1 659 72234 Y74 P S A N E V F Y N P V Q E F N
Chimpanzee Pan troglodytes XP_512420 659 72216 Y74 P S A N E V F Y N P V Q E F N
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_533897 599 65123 T83 P A E M E N G T K P C G E E R
Cat Felis silvestris
Mouse Mus musculus Q3TX08 663 72331 Y75 P S A N E V F Y N P V Q E F N
Rat Rattus norvegicus NP_001013892 440 47625
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis NP_001121226 601 66478 A74 L V V N L S E A G E D N M N S
Zebra Danio Brachydanio rerio XP_685886 672 74495 Y110 P N A N E V F Y N P V Q E F N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VK89 578 64939 E75 K Q R K K V K E Q E D E K T T
Honey Bee Apis mellifera XP_392637 501 56267 A20 I N I K E G E A E I L V N D T
Nematode Worm Caenorhab. elegans Q23270 526 58381 E44 V F Y N P V Q E F N R D L T V
Sea Urchin Strong. purpuratus XP_790648 556 62357 T74 E T K D T D D T Q Q E T V S E
Poplar Tree Populus trichocarpa XP_002330951 583 64164 E76 A S G K D A S E P A V V E E S
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LFU5 593 65826 E75 V V E K D V S E T S K E E T P
Baker's Yeast Sacchar. cerevisiae P15565 570 64034 V74 Q F N R D L S V T C I K A W D
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 N.A. 74.9 N.A. 82.8 57.9 N.A. N.A. N.A. 56.2 59.5 N.A. 41.2 39.6 35.6 42.4
Protein Similarity: 100 99.8 N.A. 77 N.A. 88 61.9 N.A. N.A. N.A. 68.1 72.6 N.A. 54.9 53.8 49 58.5
P-Site Identity: 100 100 N.A. 26.6 N.A. 100 0 N.A. N.A. N.A. 6.6 93.3 N.A. 6.6 6.6 13.3 0
P-Site Similarity: 100 100 N.A. 33.3 N.A. 100 0 N.A. N.A. N.A. 13.3 100 N.A. 26.6 20 13.3 13.3
Percent
Protein Identity: 34.2 N.A. N.A. 33.6 32.4 N.A.
Protein Similarity: 51.9 N.A. N.A. 51.9 49.7 N.A.
P-Site Identity: 20 N.A. N.A. 13.3 0 N.A.
P-Site Similarity: 33.3 N.A. N.A. 26.6 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 29 0 0 8 0 15 0 8 0 0 8 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 8 8 0 0 0 0 % C
% Asp: 0 0 0 8 22 8 8 0 0 0 15 8 0 8 8 % D
% Glu: 8 0 15 0 43 0 15 29 8 15 8 15 50 15 8 % E
% Phe: 0 15 0 0 0 0 29 0 8 0 0 0 0 29 0 % F
% Gly: 0 0 8 0 0 8 8 0 8 0 0 8 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 8 0 8 0 0 0 0 0 0 8 8 0 0 0 0 % I
% Lys: 8 0 8 29 8 0 8 0 8 0 8 8 8 0 0 % K
% Leu: 8 0 0 0 8 8 0 0 0 0 8 0 8 0 0 % L
% Met: 0 0 0 8 0 0 0 0 0 0 0 0 8 0 0 % M
% Asn: 0 15 8 43 0 8 0 0 29 8 0 8 8 8 29 % N
% Pro: 36 0 0 0 8 0 0 0 8 36 0 0 0 0 8 % P
% Gln: 8 8 0 0 0 0 8 0 15 8 0 29 0 0 0 % Q
% Arg: 0 0 8 8 0 0 0 0 0 0 8 0 0 0 8 % R
% Ser: 0 29 0 0 0 8 22 0 0 8 0 0 0 8 15 % S
% Thr: 0 8 0 0 8 0 0 15 15 0 0 8 0 22 15 % T
% Val: 15 15 8 0 0 50 0 8 0 0 36 15 8 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % W
% Tyr: 0 0 8 0 0 0 0 29 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _