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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RNF186 All Species: 12.12
Human Site: S14 Identified Species: 38.1
UniProt: Q9NXI6 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NXI6 NP_061935.1 227 24145 S14 L Q Q S Q P I S A G A T T T T
Chimpanzee Pan troglodytes XP_001160206 227 24204 S14 L Q Q S Q P I S A G A T T T T
Rhesus Macaque Macaca mulatta XP_001094241 227 24348 S14 L Q Q P Q P I S A G A T T T T
Dog Lupus familis XP_544526 286 30177 S73 P R Q P Q P V S A K A T T A T
Cat Felis silvestris
Mouse Mus musculus Q9D241 226 24686 G27 I I A L G P T G R L S I S V E
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505527 245 26659 P36 S A P G T R Q P G S P R A S A
Chicken Gallus gallus XP_001234238 168 18197
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q5EAE9 407 45251 G120 V G G R K N S G I D R S V I E
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.6 94.7 59 N.A. 66.5 N.A. N.A. 45.3 25.1 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 98.6 96 65.3 N.A. 75.7 N.A. N.A. 57.1 35.6 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 93.3 60 N.A. 6.6 N.A. N.A. 0 0 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 93.3 73.3 N.A. 26.6 N.A. N.A. 6.6 0 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 20.6 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 29.7 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 0 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 20 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 13 13 0 0 0 0 0 50 0 50 0 13 13 13 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 13 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 25 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 13 13 13 13 0 0 25 13 38 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 13 13 0 0 0 0 38 0 13 0 0 13 0 13 0 % I
% Lys: 0 0 0 0 13 0 0 0 0 13 0 0 0 0 0 % K
% Leu: 38 0 0 13 0 0 0 0 0 13 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 13 0 0 0 0 0 0 0 0 0 % N
% Pro: 13 0 13 25 0 63 0 13 0 0 13 0 0 0 0 % P
% Gln: 0 38 50 0 50 0 13 0 0 0 0 0 0 0 0 % Q
% Arg: 0 13 0 13 0 13 0 0 13 0 13 13 0 0 0 % R
% Ser: 13 0 0 25 0 0 13 50 0 13 13 13 13 13 0 % S
% Thr: 0 0 0 0 13 0 13 0 0 0 0 50 50 38 50 % T
% Val: 13 0 0 0 0 0 13 0 0 0 0 0 13 13 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _