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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RNF186
All Species:
17.27
Human Site:
Y174
Identified Species:
54.29
UniProt:
Q9NXI6
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NXI6
NP_061935.1
227
24145
Y174
I
L
I
G
P
F
I
Y
P
G
V
L
R
W
V
Chimpanzee
Pan troglodytes
XP_001160206
227
24204
Y174
I
F
I
G
P
F
I
Y
P
G
V
L
R
W
V
Rhesus Macaque
Macaca mulatta
XP_001094241
227
24348
Y174
I
L
I
G
P
F
I
Y
P
G
V
L
R
W
V
Dog
Lupus familis
XP_544526
286
30177
Y233
I
L
I
L
P
F
I
Y
P
G
I
M
R
W
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9D241
226
24686
Y173
V
L
I
L
P
F
I
Y
P
G
V
I
R
W
V
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505527
245
26659
V193
I
V
F
I
L
P
F
V
Y
P
G
V
M
K
W
Chicken
Gallus gallus
XP_001234238
168
18197
R115
E
H
P
R
A
A
A
R
S
L
Q
D
V
A
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q5EAE9
407
45251
E306
L
L
L
I
P
N
R
E
S
F
E
G
R
F
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.6
94.7
59
N.A.
66.5
N.A.
N.A.
45.3
25.1
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
98.6
96
65.3
N.A.
75.7
N.A.
N.A.
57.1
35.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
100
80
N.A.
80
N.A.
N.A.
6.6
0
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
93.3
100
93.3
N.A.
93.3
N.A.
N.A.
20
0
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.6
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
29.7
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
13
13
13
0
0
0
0
0
0
13
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
13
0
0
0
% D
% Glu:
13
0
0
0
0
0
0
13
0
0
13
0
0
0
13
% E
% Phe:
0
13
13
0
0
63
13
0
0
13
0
0
0
13
0
% F
% Gly:
0
0
0
38
0
0
0
0
0
63
13
13
0
0
0
% G
% His:
0
13
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
63
0
63
25
0
0
63
0
0
0
13
13
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
13
0
% K
% Leu:
13
63
13
25
13
0
0
0
0
13
0
38
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
13
13
0
0
% M
% Asn:
0
0
0
0
0
13
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
13
0
75
13
0
0
63
13
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
13
0
0
0
0
% Q
% Arg:
0
0
0
13
0
0
13
13
0
0
0
0
75
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
25
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
13
% T
% Val:
13
13
0
0
0
0
0
13
0
0
50
13
13
0
63
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
63
13
% W
% Tyr:
0
0
0
0
0
0
0
63
13
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _