KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PGPEP1
All Species:
24.85
Human Site:
S118
Identified Species:
49.7
UniProt:
Q9NXJ5
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NXJ5
NP_060182.1
209
23138
S118
D
G
P
E
S
I
D
S
I
I
D
M
D
A
V
Chimpanzee
Pan troglodytes
XP_523167
196
21554
V114
K
R
V
A
V
E
G
V
D
V
I
F
S
R
D
Rhesus Macaque
Macaca mulatta
XP_001115337
209
23120
S118
D
G
P
E
S
I
D
S
I
I
D
M
D
A
V
Dog
Lupus familis
XP_541939
209
23070
S118
D
G
P
E
S
I
D
S
I
I
D
M
D
A
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9ESW8
209
22916
S118
D
G
P
E
S
I
D
S
I
I
D
M
D
A
V
Rat
Rattus norvegicus
Q76IC5
209
22895
S118
D
G
P
E
S
I
D
S
I
I
D
M
D
A
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_418244
148
16020
K66
R
L
I
P
A
L
W
K
K
H
S
P
Q
L
V
Frog
Xenopus laevis
NP_001089703
210
23083
S118
G
G
P
E
C
L
H
S
I
I
D
I
D
T
V
Zebra Danio
Brachydanio rerio
NP_001018362
208
23080
S117
G
G
P
D
C
I
H
S
V
I
D
M
D
M
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001121977
194
22232
I112
K
C
P
D
E
S
N
I
K
T
E
V
L
E
T
Nematode Worm
Caenorhab. elegans
NP_001129785
201
22417
V115
S
S
E
H
E
T
L
V
S
C
I
N
C
D
F
Sea Urchin
Strong. purpuratus
XP_786904
206
22870
I118
I
I
G
G
P
D
C
I
L
S
H
I
N
M
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
40.1
99.5
93.7
N.A.
94.7
94.2
N.A.
N.A.
56.9
72.8
69.3
N.A.
N.A.
36.8
33
46.4
Protein Similarity:
100
57.8
100
95.6
N.A.
96.6
96.6
N.A.
N.A.
61.2
84.7
82.3
N.A.
N.A.
55
51.6
63.6
P-Site Identity:
100
0
100
100
N.A.
100
100
N.A.
N.A.
6.6
60
60
N.A.
N.A.
6.6
0
0
P-Site Similarity:
100
6.6
100
100
N.A.
100
100
N.A.
N.A.
20
73.3
73.3
N.A.
N.A.
33.3
0
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
9
0
0
0
0
0
0
0
0
42
9
% A
% Cys:
0
9
0
0
17
0
9
0
0
9
0
0
9
0
0
% C
% Asp:
42
0
0
17
0
9
42
0
9
0
59
0
59
9
9
% D
% Glu:
0
0
9
50
17
9
0
0
0
0
9
0
0
9
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
9
% F
% Gly:
17
59
9
9
0
0
9
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
9
0
0
17
0
0
9
9
0
0
0
0
% H
% Ile:
9
9
9
0
0
50
0
17
50
59
17
17
0
0
0
% I
% Lys:
17
0
0
0
0
0
0
9
17
0
0
0
0
0
0
% K
% Leu:
0
9
0
0
0
17
9
0
9
0
0
0
9
9
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
50
0
17
0
% M
% Asn:
0
0
0
0
0
0
9
0
0
0
0
9
9
0
0
% N
% Pro:
0
0
67
9
9
0
0
0
0
0
0
9
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% Q
% Arg:
9
9
0
0
0
0
0
0
0
0
0
0
0
9
0
% R
% Ser:
9
9
0
0
42
9
0
59
9
9
9
0
9
0
0
% S
% Thr:
0
0
0
0
0
9
0
0
0
9
0
0
0
9
9
% T
% Val:
0
0
9
0
9
0
0
17
9
9
0
9
0
0
67
% V
% Trp:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _