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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PGPEP1 All Species: 26.06
Human Site: S164 Identified Species: 52.12
UniProt: Q9NXJ5 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NXJ5 NP_060182.1 209 23138 S164 L Y Q S H G R S A F V H V P P
Chimpanzee Pan troglodytes XP_523167 196 21554 G160 G L P A S L L G R A L R V I I
Rhesus Macaque Macaca mulatta XP_001115337 209 23120 S164 L Y Q S H G R S A F V H V P P
Dog Lupus familis XP_541939 209 23070 S164 L Y Q S H G R S A F V H V P P
Cat Felis silvestris
Mouse Mus musculus Q9ESW8 209 22916 S164 L Y Q G R G R S A F V H V P P
Rat Rattus norvegicus Q76IC5 209 22895 S164 L Y R G R G R S A F V H V P P
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_418244 148 16020 V112 C P G S Q C C V E G G P E C I
Frog Xenopus laevis NP_001089703 210 23083 S164 L Y Q S C G R S V F I H V P P
Zebra Danio Brachydanio rerio NP_001018362 208 23080 S163 L F V G E G R S A F V H V P P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001121977 194 22232 K158 L C E Y I F Y K S L Q I S S K
Nematode Worm Caenorhab. elegans NP_001129785 201 22417 S161 C G F S Y F L S L H E D C S K
Sea Urchin Strong. purpuratus XP_786904 206 22870 S164 Y L S L H Q S S D S S V F I H
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 40.1 99.5 93.7 N.A. 94.7 94.2 N.A. N.A. 56.9 72.8 69.3 N.A. N.A. 36.8 33 46.4
Protein Similarity: 100 57.8 100 95.6 N.A. 96.6 96.6 N.A. N.A. 61.2 84.7 82.3 N.A. N.A. 55 51.6 63.6
P-Site Identity: 100 6.6 100 100 N.A. 86.6 80 N.A. N.A. 6.6 80 73.3 N.A. N.A. 6.6 13.3 13.3
P-Site Similarity: 100 20 100 100 N.A. 86.6 86.6 N.A. N.A. 6.6 86.6 80 N.A. N.A. 20 20 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 9 0 0 0 0 50 9 0 0 0 0 0 % A
% Cys: 17 9 0 0 9 9 9 0 0 0 0 0 9 9 0 % C
% Asp: 0 0 0 0 0 0 0 0 9 0 0 9 0 0 0 % D
% Glu: 0 0 9 0 9 0 0 0 9 0 9 0 9 0 0 % E
% Phe: 0 9 9 0 0 17 0 0 0 59 0 0 9 0 0 % F
% Gly: 9 9 9 25 0 59 0 9 0 9 9 0 0 0 0 % G
% His: 0 0 0 0 34 0 0 0 0 9 0 59 0 0 9 % H
% Ile: 0 0 0 0 9 0 0 0 0 0 9 9 0 17 17 % I
% Lys: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 17 % K
% Leu: 67 17 0 9 0 9 17 0 9 9 9 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 9 9 0 0 0 0 0 0 0 0 9 0 59 59 % P
% Gln: 0 0 42 0 9 9 0 0 0 0 9 0 0 0 0 % Q
% Arg: 0 0 9 0 17 0 59 0 9 0 0 9 0 0 0 % R
% Ser: 0 0 9 50 9 0 9 75 9 9 9 0 9 17 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 9 0 0 0 0 9 9 0 50 9 67 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 9 50 0 9 9 0 9 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _