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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PGPEP1 All Species: 19.09
Human Site: S66 Identified Species: 38.18
UniProt: Q9NXJ5 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NXJ5 NP_060182.1 209 23138 S66 P A L W E K H S P Q L V V H V
Chimpanzee Pan troglodytes XP_523167 196 21554 I62 M D T A A K A I I L E Q S G K
Rhesus Macaque Macaca mulatta XP_001115337 209 23120 S66 P A L W E K H S P Q L V V H V
Dog Lupus familis XP_541939 209 23070 S66 P A L W E K H S P Q L V V H V
Cat Felis silvestris
Mouse Mus musculus Q9ESW8 209 22916 S66 P A L W E K H S P Q L V V H V
Rat Rattus norvegicus Q76IC5 209 22895 S66 P A L W E K H S P Q L V V H V
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_418244 148 16020 A14 G P H L L P A A R F G P F G E
Frog Xenopus laevis NP_001089703 210 23083 K66 P A L R K K H K P K V T V H V
Zebra Danio Brachydanio rerio NP_001018362 208 23080 L65 P S L W K D H L P Q L V V H V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001121977 194 22232 T60 V S Y E D V I T Y I P K F W K
Nematode Worm Caenorhab. elegans NP_001129785 201 22417 K63 P E L W N E H K P D L V I H L
Sea Urchin Strong. purpuratus XP_786904 206 22870 N66 P A L W K E Y N P V L M V H V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 40.1 99.5 93.7 N.A. 94.7 94.2 N.A. N.A. 56.9 72.8 69.3 N.A. N.A. 36.8 33 46.4
Protein Similarity: 100 57.8 100 95.6 N.A. 96.6 96.6 N.A. N.A. 61.2 84.7 82.3 N.A. N.A. 55 51.6 63.6
P-Site Identity: 100 6.6 100 100 N.A. 100 100 N.A. N.A. 0 60 73.3 N.A. N.A. 0 53.3 60
P-Site Similarity: 100 6.6 100 100 N.A. 100 100 N.A. N.A. 6.6 80 86.6 N.A. N.A. 20 73.3 93.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 59 0 9 9 0 17 9 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 9 0 0 9 9 0 0 0 9 0 0 0 0 0 % D
% Glu: 0 9 0 9 42 17 0 0 0 0 9 0 0 0 9 % E
% Phe: 0 0 0 0 0 0 0 0 0 9 0 0 17 0 0 % F
% Gly: 9 0 0 0 0 0 0 0 0 0 9 0 0 17 0 % G
% His: 0 0 9 0 0 0 67 0 0 0 0 0 0 75 0 % H
% Ile: 0 0 0 0 0 0 9 9 9 9 0 0 9 0 0 % I
% Lys: 0 0 0 0 25 59 0 17 0 9 0 9 0 0 17 % K
% Leu: 0 0 75 9 9 0 0 9 0 9 67 0 0 0 9 % L
% Met: 9 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % M
% Asn: 0 0 0 0 9 0 0 9 0 0 0 0 0 0 0 % N
% Pro: 75 9 0 0 0 9 0 0 75 0 9 9 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 50 0 9 0 0 0 % Q
% Arg: 0 0 0 9 0 0 0 0 9 0 0 0 0 0 0 % R
% Ser: 0 17 0 0 0 0 0 42 0 0 0 0 9 0 0 % S
% Thr: 0 0 9 0 0 0 0 9 0 0 0 9 0 0 0 % T
% Val: 9 0 0 0 0 9 0 0 0 9 9 59 67 0 67 % V
% Trp: 0 0 0 67 0 0 0 0 0 0 0 0 0 9 0 % W
% Tyr: 0 0 9 0 0 0 9 0 9 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _