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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FBXL12
All Species:
6.97
Human Site:
S124
Identified Species:
19.17
UniProt:
Q9NXK8
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NXK8
NP_060173.1
326
37026
S124
V
P
I
T
S
L
P
S
T
L
R
T
L
E
L
Chimpanzee
Pan troglodytes
XP_512355
273
30473
R107
L
E
C
I
V
L
D
R
V
P
A
F
R
D
E
Rhesus Macaque
Macaca mulatta
XP_001087353
444
49825
P191
F
D
V
V
S
L
C
P
N
L
E
H
L
D
V
Dog
Lupus familis
XP_542082
448
49988
C246
V
P
I
T
S
L
P
C
T
L
R
T
L
E
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9EPX5
326
37213
S124
V
P
I
T
S
L
P
S
T
L
R
T
L
E
L
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001235272
352
39687
P165
I
P
Y
N
S
L
P
P
S
L
T
T
L
E
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001073511
489
54202
P236
F
E
V
V
S
R
C
P
N
L
E
H
L
D
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_733291
515
58862
T263
V
T
G
S
T
L
K
T
L
I
Q
R
S
K
R
Honey Bee
Apis mellifera
XP_397111
517
59162
N181
G
F
M
R
K
I
Y
N
F
I
N
G
L
E
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.7
20.2
70.3
N.A.
93.2
N.A.
N.A.
N.A.
35.2
N.A.
20.4
N.A.
21.5
22.8
N.A.
N.A.
Protein Similarity:
100
83.7
38.2
71.6
N.A.
96.6
N.A.
N.A.
N.A.
49.1
N.A.
34.9
N.A.
36.7
38.2
N.A.
N.A.
P-Site Identity:
100
6.6
26.6
93.3
N.A.
100
N.A.
N.A.
N.A.
60
N.A.
20
N.A.
13.3
13.3
N.A.
N.A.
P-Site Similarity:
100
20
46.6
93.3
N.A.
100
N.A.
N.A.
N.A.
73.3
N.A.
40
N.A.
53.3
46.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% A
% Cys:
0
0
12
0
0
0
23
12
0
0
0
0
0
0
0
% C
% Asp:
0
12
0
0
0
0
12
0
0
0
0
0
0
34
0
% D
% Glu:
0
23
0
0
0
0
0
0
0
0
23
0
0
56
12
% E
% Phe:
23
12
0
0
0
0
0
0
12
0
0
12
0
0
0
% F
% Gly:
12
0
12
0
0
0
0
0
0
0
0
12
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
23
0
0
0
% H
% Ile:
12
0
34
12
0
12
0
0
0
23
0
0
0
0
12
% I
% Lys:
0
0
0
0
12
0
12
0
0
0
0
0
0
12
0
% K
% Leu:
12
0
0
0
0
78
0
0
12
67
0
0
78
0
45
% L
% Met:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
12
0
0
0
12
23
0
12
0
0
0
0
% N
% Pro:
0
45
0
0
0
0
45
34
0
12
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% Q
% Arg:
0
0
0
12
0
12
0
12
0
0
34
12
12
0
12
% R
% Ser:
0
0
0
12
67
0
0
23
12
0
0
0
12
0
0
% S
% Thr:
0
12
0
34
12
0
0
12
34
0
12
45
0
0
0
% T
% Val:
45
0
23
23
12
0
0
0
12
0
0
0
0
0
23
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
12
0
0
0
12
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _