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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MCM9 All Species: 7.88
Human Site: S883 Identified Species: 15.76
UniProt: Q9NXL9 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.27
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NXL9 NP_694987.1 1143 127338 S883 P Q S T P V H S P D R R L D S
Chimpanzee Pan troglodytes XP_001163603 1143 127281 S883 P Q S P P V H S P D R M L D S
Rhesus Macaque Macaca mulatta XP_001110306 1142 127490 R882 P Q S T P V H R P D R M L D S
Dog Lupus familis XP_541221 1141 126374 S882 A P S S P V C S P Q G T L E T
Cat Felis silvestris
Mouse Mus musculus Q2KHI9 1134 125796 T877 G S G K R S G T P K R K R R K
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis Q6NRM6 1143 126576 K878 I V T E H V S K K W R R I N K
Zebra Danio Brachydanio rerio XP_683173 660 73264 K426 I D E F N S I K E H D R T S I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_391969 625 70198 Q391 E F T T M S S Q D R T S V H E
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_785765 1217 134283 G894 E K R K K V N G S G V S K D G
Poplar Tree Populus trichocarpa XP_002325759 738 82610 V504 E E Y I N Q L V V T G R L S L
Maize Zea mays Q43704 768 85163 D534 A A I F V K Y D R M L H G Q D
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FL33 776 86338 K542 K R G Q T H D K T L T I K F L
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.6 95.7 81.3 N.A. 74.7 N.A. N.A. N.A. N.A. 53.1 44.4 N.A. N.A. 26.4 N.A. 41.3
Protein Similarity: 100 98.9 97.3 87.6 N.A. 83.4 N.A. N.A. N.A. N.A. 65.4 50.5 N.A. N.A. 38.1 N.A. 57.9
P-Site Identity: 100 86.6 86.6 40 N.A. 13.3 N.A. N.A. N.A. N.A. 20 6.6 N.A. N.A. 6.6 N.A. 13.3
P-Site Similarity: 100 86.6 86.6 60 N.A. 26.6 N.A. N.A. N.A. N.A. 40 6.6 N.A. N.A. 20 N.A. 26.6
Percent
Protein Identity: 29.6 21.6 N.A. 21.9 N.A. N.A.
Protein Similarity: 41.9 37.9 N.A. 37.4 N.A. N.A.
P-Site Identity: 13.3 0 N.A. 0 N.A. N.A.
P-Site Similarity: 20 6.6 N.A. 6.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 17 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % C
% Asp: 0 9 0 0 0 0 9 9 9 25 9 0 0 34 9 % D
% Glu: 25 9 9 9 0 0 0 0 9 0 0 0 0 9 9 % E
% Phe: 0 9 0 17 0 0 0 0 0 0 0 0 0 9 0 % F
% Gly: 9 0 17 0 0 0 9 9 0 9 17 0 9 0 9 % G
% His: 0 0 0 0 9 9 25 0 0 9 0 9 0 9 0 % H
% Ile: 17 0 9 9 0 0 9 0 0 0 0 9 9 0 9 % I
% Lys: 9 9 0 17 9 9 0 25 9 9 0 9 17 0 17 % K
% Leu: 0 0 0 0 0 0 9 0 0 9 9 0 42 0 17 % L
% Met: 0 0 0 0 9 0 0 0 0 9 0 17 0 0 0 % M
% Asn: 0 0 0 0 17 0 9 0 0 0 0 0 0 9 0 % N
% Pro: 25 9 0 9 34 0 0 0 42 0 0 0 0 0 0 % P
% Gln: 0 25 0 9 0 9 0 9 0 9 0 0 0 9 0 % Q
% Arg: 0 9 9 0 9 0 0 9 9 9 42 34 9 9 0 % R
% Ser: 0 9 34 9 0 25 17 25 9 0 0 17 0 17 25 % S
% Thr: 0 0 17 25 9 0 0 9 9 9 17 9 9 0 9 % T
% Val: 0 9 0 0 9 50 0 9 9 0 9 0 9 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % W
% Tyr: 0 0 9 0 0 0 9 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _