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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MCM9 All Species: 8.79
Human Site: T673 Identified Species: 17.58
UniProt: Q9NXL9 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NXL9 NP_694987.1 1143 127338 T673 R V L E V E T T P G S L R N G
Chimpanzee Pan troglodytes XP_001163603 1143 127281 T673 Q V L E V E T T P G S L R N G
Rhesus Macaque Macaca mulatta XP_001110306 1142 127490 T673 P V L E V E T T P G S L R N G
Dog Lupus familis XP_541221 1141 126374 N673 Q A V E V E T N P G S S K S D
Cat Felis silvestris
Mouse Mus musculus Q2KHI9 1134 125796 A673 H S L E E E V A P G S C R N D
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis Q6NRM6 1143 126576 V674 G E S A T N L V G H K V V H S
Zebra Danio Brachydanio rerio XP_683173 660 73264 P223 K L S V G S I P R S M L I I L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_391969 625 70198 E188 D T N K S L T E E L R I I L L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_785765 1217 134283 A690 E K E T D K E A I A N E T L D
Poplar Tree Populus trichocarpa XP_002325759 738 82610 F301 V I M K F K Q F W S D F N D T
Maize Zea mays Q43704 768 85163 L330 N L K N G T H L R G D I N M M
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FL33 776 86338 V339 M M V G D P S V A K S Q L L R
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.6 95.7 81.3 N.A. 74.7 N.A. N.A. N.A. N.A. 53.1 44.4 N.A. N.A. 26.4 N.A. 41.3
Protein Similarity: 100 98.9 97.3 87.6 N.A. 83.4 N.A. N.A. N.A. N.A. 65.4 50.5 N.A. N.A. 38.1 N.A. 57.9
P-Site Identity: 100 93.3 93.3 46.6 N.A. 53.3 N.A. N.A. N.A. N.A. 0 6.6 N.A. N.A. 6.6 N.A. 0
P-Site Similarity: 100 100 93.3 73.3 N.A. 53.3 N.A. N.A. N.A. N.A. 13.3 20 N.A. N.A. 20 N.A. 13.3
Percent
Protein Identity: 29.6 21.6 N.A. 21.9 N.A. N.A.
Protein Similarity: 41.9 37.9 N.A. 37.4 N.A. N.A.
P-Site Identity: 0 6.6 N.A. 6.6 N.A. N.A.
P-Site Similarity: 33.3 20 N.A. 26.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 0 9 0 0 0 17 9 9 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % C
% Asp: 9 0 0 0 17 0 0 0 0 0 17 0 0 9 25 % D
% Glu: 9 9 9 42 9 42 9 9 9 0 0 9 0 0 0 % E
% Phe: 0 0 0 0 9 0 0 9 0 0 0 9 0 0 0 % F
% Gly: 9 0 0 9 17 0 0 0 9 50 0 0 0 0 25 % G
% His: 9 0 0 0 0 0 9 0 0 9 0 0 0 9 0 % H
% Ile: 0 9 0 0 0 0 9 0 9 0 0 17 17 9 0 % I
% Lys: 9 9 9 17 0 17 0 0 0 9 9 0 9 0 0 % K
% Leu: 0 17 34 0 0 9 9 9 0 9 0 34 9 25 17 % L
% Met: 9 9 9 0 0 0 0 0 0 0 9 0 0 9 9 % M
% Asn: 9 0 9 9 0 9 0 9 0 0 9 0 17 34 0 % N
% Pro: 9 0 0 0 0 9 0 9 42 0 0 0 0 0 0 % P
% Gln: 17 0 0 0 0 0 9 0 0 0 0 9 0 0 0 % Q
% Arg: 9 0 0 0 0 0 0 0 17 0 9 0 34 0 9 % R
% Ser: 0 9 17 0 9 9 9 0 0 17 50 9 0 9 9 % S
% Thr: 0 9 0 9 9 9 42 25 0 0 0 0 9 0 9 % T
% Val: 9 25 17 9 34 0 9 17 0 0 0 9 9 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _