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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MCM9
All Species:
22.73
Human Site:
Y527
Identified Species:
45.45
UniProt:
Q9NXL9
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NXL9
NP_694987.1
1143
127338
Y527
S
M
E
K
M
K
T
Y
F
C
L
I
R
N
L
Chimpanzee
Pan troglodytes
XP_001163603
1143
127281
Y527
S
M
E
K
M
K
T
Y
F
C
L
I
R
N
L
Rhesus Macaque
Macaca mulatta
XP_001110306
1142
127490
Y527
S
M
E
K
M
K
T
Y
F
C
L
I
R
N
L
Dog
Lupus familis
XP_541221
1141
126374
Y527
S
M
E
K
M
K
T
Y
F
C
L
I
R
N
L
Cat
Felis silvestris
Mouse
Mus musculus
Q2KHI9
1134
125796
Y527
S
M
E
K
M
K
T
Y
F
C
L
I
R
N
L
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6NRM6
1143
126576
Y528
S
M
E
K
M
K
T
Y
F
C
L
I
K
N
L
Zebra Danio
Brachydanio rerio
XP_683173
660
73264
Q78
P
I
F
D
N
A
L
Q
R
A
A
Q
A
I
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_391969
625
70198
V43
L
F
E
D
D
A
D
V
A
Q
K
I
L
Q
Y
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785765
1217
134283
W536
G
A
P
A
S
D
L
W
S
I
E
K
M
Q
T
Poplar Tree
Populus trichocarpa
XP_002325759
738
82610
M156
K
M
Y
E
G
E
R
M
Y
Q
C
R
K
C
K
Maize
Zea mays
Q43704
768
85163
G185
N
L
L
V
T
E
Y
G
M
C
E
Y
K
D
H
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FL33
776
86338
E194
H
Q
T
L
S
I
Q
E
V
P
E
N
A
A
P
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.6
95.7
81.3
N.A.
74.7
N.A.
N.A.
N.A.
N.A.
53.1
44.4
N.A.
N.A.
26.4
N.A.
41.3
Protein Similarity:
100
98.9
97.3
87.6
N.A.
83.4
N.A.
N.A.
N.A.
N.A.
65.4
50.5
N.A.
N.A.
38.1
N.A.
57.9
P-Site Identity:
100
100
100
100
N.A.
100
N.A.
N.A.
N.A.
N.A.
93.3
0
N.A.
N.A.
13.3
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
100
N.A.
N.A.
N.A.
N.A.
100
6.6
N.A.
N.A.
13.3
N.A.
6.6
Percent
Protein Identity:
29.6
21.6
N.A.
21.9
N.A.
N.A.
Protein Similarity:
41.9
37.9
N.A.
37.4
N.A.
N.A.
P-Site Identity:
6.6
6.6
N.A.
0
N.A.
N.A.
P-Site Similarity:
33.3
40
N.A.
0
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
9
0
17
0
0
9
9
9
0
17
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
59
9
0
0
9
0
% C
% Asp:
0
0
0
17
9
9
9
0
0
0
0
0
0
9
0
% D
% Glu:
0
0
59
9
0
17
0
9
0
0
25
0
0
0
0
% E
% Phe:
0
9
9
0
0
0
0
0
50
0
0
0
0
0
0
% F
% Gly:
9
0
0
0
9
0
0
9
0
0
0
0
0
0
0
% G
% His:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% H
% Ile:
0
9
0
0
0
9
0
0
0
9
0
59
0
9
0
% I
% Lys:
9
0
0
50
0
50
0
0
0
0
9
9
25
0
9
% K
% Leu:
9
9
9
9
0
0
17
0
0
0
50
0
9
0
50
% L
% Met:
0
59
0
0
50
0
0
9
9
0
0
0
9
0
0
% M
% Asn:
9
0
0
0
9
0
0
0
0
0
0
9
0
50
0
% N
% Pro:
9
0
9
0
0
0
0
0
0
9
0
0
0
0
9
% P
% Gln:
0
9
0
0
0
0
9
9
0
17
0
9
0
17
0
% Q
% Arg:
0
0
0
0
0
0
9
0
9
0
0
9
42
0
0
% R
% Ser:
50
0
0
0
17
0
0
0
9
0
0
0
0
0
9
% S
% Thr:
0
0
9
0
9
0
50
0
0
0
0
0
0
0
9
% T
% Val:
0
0
0
9
0
0
0
9
9
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% W
% Tyr:
0
0
9
0
0
0
9
50
9
0
0
9
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _