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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GDAP2 All Species: 27.27
Human Site: S446 Identified Species: 46.15
UniProt: Q9NXN4 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NXN4 NP_001129061.1 497 56225 S446 F F T T F S V S G L K D K I H
Chimpanzee Pan troglodytes XP_001144135 497 56247 S446 F F T T F S V S G L K D K I H
Rhesus Macaque Macaca mulatta XP_001104476 296 33809 G246 F T T F S V S G L K D K I H H
Dog Lupus familis XP_533021 497 56263 S446 F F T T F S V S G L K D K I H
Cat Felis silvestris
Mouse Mus musculus Q9DBL2 498 56250 S447 F F T T F S V S G L K D K I H
Rat Rattus norvegicus Q66H63 497 56112 S446 F F T T F S V S G L K D K I H
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512063 764 83960 G520 P Y R P G C S G P G L C W L C
Chicken Gallus gallus XP_423602 578 65530 S527 F F T T F T V S G L K D K I H
Frog Xenopus laevis Q5XGM5 496 56135 S445 F F T T F T V S G L K D K V H
Zebra Danio Brachydanio rerio Q66HX8 504 57497 F452 S T W F F T T F S V S G L K D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q7JUR6 540 61422 P490 W F T T F M A P A I K A K V H
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002315014 561 63517 N505 A L Q V F V D N V T W K K V V
Maize Zea mays NP_001152046 579 63936 G521 A M Q L F V D G E V W K K V V
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_564960 562 63287 N506 T M Q F F V D N V V W K K V V
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 58.9 96.5 N.A. 94.7 95.1 N.A. 47.6 74.3 75.2 73.6 N.A. 37.7 N.A. N.A. N.A.
Protein Similarity: 100 100 59.3 98.3 N.A. 97.3 98.1 N.A. 53.2 80 87.3 85.3 N.A. 59 N.A. N.A. N.A.
P-Site Identity: 100 100 20 100 N.A. 100 100 N.A. 0 93.3 86.6 6.6 N.A. 46.6 N.A. N.A. N.A.
P-Site Similarity: 100 100 20 100 N.A. 100 100 N.A. 13.3 100 100 20 N.A. 66.6 N.A. N.A. N.A.
Percent
Protein Identity: 32.4 33.3 N.A. 32.3 N.A. N.A.
Protein Similarity: 51.8 50 N.A. 50.3 N.A. N.A.
P-Site Identity: 13.3 13.3 N.A. 13.3 N.A. N.A.
P-Site Similarity: 26.6 26.6 N.A. 33.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 15 0 0 0 0 0 8 0 8 0 0 8 0 0 0 % A
% Cys: 0 0 0 0 0 8 0 0 0 0 0 8 0 0 8 % C
% Asp: 0 0 0 0 0 0 22 0 0 0 8 50 0 0 8 % D
% Glu: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % E
% Phe: 58 58 0 22 86 0 0 8 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 8 0 0 22 50 8 0 8 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 65 % H
% Ile: 0 0 0 0 0 0 0 0 0 8 0 0 8 43 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 8 58 29 79 8 0 % K
% Leu: 0 8 0 8 0 0 0 0 8 50 8 0 8 8 0 % L
% Met: 0 15 0 0 0 8 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 15 0 0 0 0 0 0 0 % N
% Pro: 8 0 0 8 0 0 0 8 8 0 0 0 0 0 0 % P
% Gln: 0 0 22 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 8 0 0 0 8 36 15 50 8 0 8 0 0 0 0 % S
% Thr: 8 15 65 58 0 22 8 0 0 8 0 0 0 0 0 % T
% Val: 0 0 0 8 0 29 50 0 15 22 0 0 0 36 22 % V
% Trp: 8 0 8 0 0 0 0 0 0 0 22 0 8 0 0 % W
% Tyr: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _