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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: BRE All Species: 22.73
Human Site: Y216 Identified Species: 35.71
UniProt: Q9NXR7 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NXR7 NP_004890.2 383 43552 Y216 D T E A T Q V Y P K L Y L S P
Chimpanzee Pan troglodytes XP_001160523 536 59996 Y216 D T E A T Q V Y P K L Y L S P
Rhesus Macaque Macaca mulatta XP_001100014 383 43561 Y216 D T E A T Q V Y P K L Y L S P
Dog Lupus familis XP_850681 383 43558 Y216 D T E A T Q V Y P K L Y L S P
Cat Felis silvestris
Mouse Mus musculus Q8K3W0 383 43526 Y216 D T E A T Q V Y P K L Y L S P
Rat Rattus norvegicus Q6P7Q1 383 43540 Y216 D T E A T Q V Y P K L Y L S P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508890 383 43405 F216 D A E A T Q V F P K L Y L S P
Chicken Gallus gallus Q5ZML0 383 43411 F216 D A E A T Q V F P K L Y L S P
Frog Xenopus laevis Q6GPL9 384 43573 F216 D A E A T Q V F P K L F L S P
Zebra Danio Brachydanio rerio Q568D5 386 43811 F219 D A E A T Q V F P K L Y L S P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_396044 354 40909 D207 L V T F S G T D W N R I T S Q
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_796419 304 34235 E157 T S H F T D V E V H Q V Q K T
Poplar Tree Populus trichocarpa XP_002300702 379 43746 P211 Y A P A T S A P R L K L M C T
Maize Zea mays NP_001149020 393 43831 P224 Y S S M P S A P R L K L I S T
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_199062 382 44099 R215 E A A P S A P R L K L V S Y Y
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 70.1 99.7 99.4 N.A. 99.2 98.9 N.A. 96.8 97.6 92.4 83.9 N.A. N.A. 33.1 N.A. 35.7
Protein Similarity: 100 70.3 99.7 99.7 N.A. 99.4 99.4 N.A. 98.4 98.6 95.5 91.7 N.A. N.A. 51.9 N.A. 54
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 86.6 86.6 80 86.6 N.A. N.A. 6.6 N.A. 13.3
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 93.3 93.3 93.3 93.3 N.A. N.A. 13.3 N.A. 20
Percent
Protein Identity: 28.7 28.5 N.A. 27.4 N.A. N.A.
Protein Similarity: 47.5 47.3 N.A. 46.7 N.A. N.A.
P-Site Identity: 13.3 6.6 N.A. 13.3 N.A. N.A.
P-Site Similarity: 20 20 N.A. 26.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 40 7 74 0 7 14 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 7 0 % C
% Asp: 67 0 0 0 0 7 0 7 0 0 0 0 0 0 0 % D
% Glu: 7 0 67 0 0 0 0 7 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 14 0 0 0 27 0 0 0 7 0 0 0 % F
% Gly: 0 0 0 0 0 7 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 7 0 0 0 0 0 0 7 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 7 7 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 74 14 0 0 7 0 % K
% Leu: 7 0 0 0 0 0 0 0 7 14 74 14 67 0 0 % L
% Met: 0 0 0 7 0 0 0 0 0 0 0 0 7 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 7 0 0 0 0 0 % N
% Pro: 0 0 7 7 7 0 7 14 67 0 0 0 0 0 67 % P
% Gln: 0 0 0 0 0 67 0 0 0 0 7 0 7 0 7 % Q
% Arg: 0 0 0 0 0 0 0 7 14 0 7 0 0 0 0 % R
% Ser: 0 14 7 0 14 14 0 0 0 0 0 0 7 80 0 % S
% Thr: 7 40 7 0 80 0 7 0 0 0 0 0 7 0 20 % T
% Val: 0 7 0 0 0 0 74 0 7 0 0 14 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 7 0 0 0 0 0 0 % W
% Tyr: 14 0 0 0 0 0 0 40 0 0 0 60 0 7 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _