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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ING3 All Species: 30.3
Human Site: S140 Identified Species: 60.61
UniProt: Q9NXR8 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NXR8 NP_061944.2 418 46743 S140 V N N H H A H S H T P V E K R
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001082715 370 41702 K96 L V D R H L R K L D Q E L A K
Dog Lupus familis XP_532530 418 46766 S140 V N N H H A H S H T P V E K R
Cat Felis silvestris
Mouse Mus musculus Q8VEK6 421 46828 S140 V N N H H A H S H T P V E K R
Rat Rattus norvegicus Q498T3 421 46906 S140 V N N H H A H S H T P V E K R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509240 539 58659 S263 V N N H H A H S H T P V E K R
Chicken Gallus gallus Q5ZK36 417 46548 S140 V N N H H A H S H T P V E K R
Frog Xenopus laevis Q7ZX31 416 46165 S140 V N N H H V H S H S S G E K R
Zebra Danio Brachydanio rerio NP_957231 416 46555 S140 V N N H H V H S H T T V E K R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_573316 686 70628 L197 S S I S T A Q L G S S Q R H R
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001191966 285 31785 I11 L E D Y L E M I E Q L P I E L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P50947 330 37006 K55 E R I D K F L K K D F N K D H
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 83.2 99 N.A. 95.4 96.6 N.A. 68.6 91.8 86.8 83.4 N.A. 33.6 N.A. N.A. 34.2
Protein Similarity: 100 N.A. 86.1 99 N.A. 96.1 97.1 N.A. 73 96.1 92.3 91.3 N.A. 44 N.A. N.A. 50.9
P-Site Identity: 100 N.A. 6.6 100 N.A. 100 100 N.A. 100 100 73.3 86.6 N.A. 13.3 N.A. N.A. 0
P-Site Similarity: 100 N.A. 26.6 100 N.A. 100 100 N.A. 100 100 80 86.6 N.A. 26.6 N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 22.2 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 39.2 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 59 0 0 0 0 0 0 0 9 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 17 9 0 0 0 0 0 17 0 0 0 9 0 % D
% Glu: 9 9 0 0 0 9 0 0 9 0 0 9 67 9 0 % E
% Phe: 0 0 0 0 0 9 0 0 0 0 9 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 9 0 0 9 0 0 0 % G
% His: 0 0 0 67 75 0 67 0 67 0 0 0 0 9 9 % H
% Ile: 0 0 17 0 0 0 0 9 0 0 0 0 9 0 0 % I
% Lys: 0 0 0 0 9 0 0 17 9 0 0 0 9 67 9 % K
% Leu: 17 0 0 0 9 9 9 9 9 0 9 0 9 0 9 % L
% Met: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % M
% Asn: 0 67 67 0 0 0 0 0 0 0 0 9 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 50 9 0 0 0 % P
% Gln: 0 0 0 0 0 0 9 0 0 9 9 9 0 0 0 % Q
% Arg: 0 9 0 9 0 0 9 0 0 0 0 0 9 0 75 % R
% Ser: 9 9 0 9 0 0 0 67 0 17 17 0 0 0 0 % S
% Thr: 0 0 0 0 9 0 0 0 0 59 9 0 0 0 0 % T
% Val: 67 9 0 0 0 17 0 0 0 0 0 59 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _