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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ING3 All Species: 28.79
Human Site: S246 Identified Species: 57.58
UniProt: Q9NXR8 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NXR8 NP_061944.2 418 46743 S246 M K E G R R T S S L K A S Y E
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001082715 370 41702 V202 S S N N A Y N V N S S Q P L G
Dog Lupus familis XP_532530 418 46766 S246 M K E G R R T S S L K A S Y E
Cat Felis silvestris
Mouse Mus musculus Q8VEK6 421 46828 S246 M K E G R R T S S L K A S Y E
Rat Rattus norvegicus Q498T3 421 46906 S246 M K E G R R T S S L K A S Y E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509240 539 58659 S369 M K E G R R T S S L K A S Y E
Chicken Gallus gallus Q5ZK36 417 46548 S246 M K E G R R T S S L K A S Y E
Frog Xenopus laevis Q7ZX31 416 46165 S246 M K E G R R T S S L K A S Y E
Zebra Danio Brachydanio rerio NP_957231 416 46555 T246 Q M K E G R R T S S L K A S Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_573316 686 70628 G303 S S L A T G T G S L V R Q L P
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001191966 285 31785 E117 A D H A G I T E V L E R R S L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P50947 330 37006 A161 K S E S R R E A M A A N R R Q
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 83.2 99 N.A. 95.4 96.6 N.A. 68.6 91.8 86.8 83.4 N.A. 33.6 N.A. N.A. 34.2
Protein Similarity: 100 N.A. 86.1 99 N.A. 96.1 97.1 N.A. 73 96.1 92.3 91.3 N.A. 44 N.A. N.A. 50.9
P-Site Identity: 100 N.A. 0 100 N.A. 100 100 N.A. 100 100 100 13.3 N.A. 20 N.A. N.A. 13.3
P-Site Similarity: 100 N.A. 6.6 100 N.A. 100 100 N.A. 100 100 100 33.3 N.A. 20 N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. 22.2 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 39.2 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 20 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 0 17 9 0 0 9 0 9 9 59 9 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 67 9 0 0 9 9 0 0 9 0 0 0 59 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 59 17 9 0 9 0 0 0 0 0 0 9 % G
% His: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % I
% Lys: 9 59 9 0 0 0 0 0 0 0 59 9 0 0 0 % K
% Leu: 0 0 9 0 0 0 0 0 0 75 9 0 0 17 9 % L
% Met: 59 9 0 0 0 0 0 0 9 0 0 0 0 0 0 % M
% Asn: 0 0 9 9 0 0 9 0 9 0 0 9 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 9 % P
% Gln: 9 0 0 0 0 0 0 0 0 0 0 9 9 0 9 % Q
% Arg: 0 0 0 0 67 75 9 0 0 0 0 17 17 9 0 % R
% Ser: 17 25 0 9 0 0 0 59 75 17 9 0 59 17 0 % S
% Thr: 0 0 0 0 9 0 75 9 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 9 9 0 9 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 9 0 0 0 0 0 0 0 59 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _