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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: QPCTL All Species: 11.82
Human Site: T277 Identified Species: 32.5
UniProt: Q9NXS2 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NXS2 NP_001156849.1 382 42924 T277 L L G A P N P T F Y S H F P R
Chimpanzee Pan troglodytes XP_001167364 361 40915 T256 L I G A P N P T F P N F F P N
Rhesus Macaque Macaca mulatta XP_001110995 382 42719 T277 L L G A P N P T F Y S H F P R
Dog Lupus familis XP_541552 383 42885 N278 L L G A P N P N F Y S H F P H
Cat Felis silvestris
Mouse Mus musculus Q8BH73 383 42673 I278 L L G A S S P I F F S H F P R
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518182 448 49702 S343 L L G A P G L S I H S H F P R
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001921878 391 44216 M286 L I G A A D P M F V N H F D N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_788551 352 40318 A234 L L G A P D P A F Y S F F E N
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P43599 363 41013 L240 G S G E E E P L V P S Y Y A E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 48.1 98.4 88.5 N.A. 84 N.A. N.A. 54.2 N.A. N.A. 48.5 N.A. 41.3 N.A. N.A. N.A.
Protein Similarity: 100 62 98.9 91.1 N.A. 89.3 N.A. N.A. 63.8 N.A. N.A. 63.1 N.A. 57 N.A. N.A. N.A.
P-Site Identity: 100 66.6 100 86.6 N.A. 73.3 N.A. N.A. 66.6 N.A. N.A. 46.6 N.A. 66.6 N.A. N.A. N.A.
P-Site Similarity: 100 80 100 86.6 N.A. 86.6 N.A. N.A. 80 N.A. N.A. 66.6 N.A. 73.3 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 25.3 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 42.1 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 20 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 89 12 0 0 12 0 0 0 0 0 12 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 23 0 0 0 0 0 0 0 12 0 % D
% Glu: 0 0 0 12 12 12 0 0 0 0 0 0 0 12 12 % E
% Phe: 0 0 0 0 0 0 0 0 78 12 0 23 89 0 0 % F
% Gly: 12 0 100 0 0 12 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 12 0 67 0 0 12 % H
% Ile: 0 23 0 0 0 0 0 12 12 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 89 67 0 0 0 0 12 12 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 12 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 45 0 12 0 0 23 0 0 0 34 % N
% Pro: 0 0 0 0 67 0 89 0 0 23 0 0 0 67 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 45 % R
% Ser: 0 12 0 0 12 12 0 12 0 0 78 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 34 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 12 12 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 45 0 12 12 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _