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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KLHL28
All Species:
23.94
Human Site:
S18
Identified Species:
43.89
UniProt:
Q9NXS3
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NXS3
NP_060128.2
571
64192
S18
A
N
L
T
H
L
H
S
E
Q
L
L
Q
G
L
Chimpanzee
Pan troglodytes
XP_001149345
684
76181
T129
S
D
K
H
P
R
Q
T
L
E
V
I
N
L
L
Rhesus Macaque
Macaca mulatta
XP_001095031
571
64184
S18
A
N
L
T
H
L
H
S
E
Q
L
L
Q
G
L
Dog
Lupus familis
XP_547790
571
64226
S18
A
N
L
T
H
L
H
S
E
Q
L
L
Q
G
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9CR40
571
64107
S18
A
N
L
T
H
L
H
S
E
Q
L
L
Q
G
L
Rat
Rattus norvegicus
Q8K430
640
69714
Y73
A
H
N
S
K
R
H
Y
H
D
A
F
V
A
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513616
571
64248
S18
A
N
L
T
P
L
H
S
E
Q
L
L
Q
G
L
Chicken
Gallus gallus
Q5ZI33
586
66177
E23
K
K
L
A
A
R
E
E
A
K
L
L
A
G
F
Frog
Xenopus laevis
Q6NRH0
564
63190
S21
S
I
L
N
T
M
N
S
L
R
K
S
Q
T
L
Zebra Danio
Brachydanio rerio
Q5U374
564
62914
A21
S
I
L
N
A
M
N
A
L
R
K
S
N
T
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VUU5
623
68905
M64
V
T
L
T
E
L
N
M
L
R
R
H
R
E
L
Honey Bee
Apis mellifera
XP_397065
620
68991
V71
A
T
L
T
E
L
N
V
L
R
R
H
R
E
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780225
597
66997
A42
S
S
E
V
S
G
H
A
R
M
V
L
R
E
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
36.9
99.4
99.1
N.A.
97
38.4
N.A.
93.1
32.7
38.7
38.3
N.A.
40.1
40
N.A.
46.2
Protein Similarity:
100
53
99.4
99.6
N.A.
99.1
53.4
N.A.
96.6
50.5
56.7
57
N.A.
56.1
56.2
N.A.
65.1
P-Site Identity:
100
6.6
100
100
N.A.
100
13.3
N.A.
93.3
26.6
26.6
13.3
N.A.
26.6
33.3
N.A.
13.3
P-Site Similarity:
100
46.6
100
100
N.A.
100
33.3
N.A.
93.3
33.3
53.3
46.6
N.A.
46.6
53.3
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
54
0
0
8
16
0
0
16
8
0
8
0
8
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
0
0
0
0
0
0
8
0
0
0
0
0
% D
% Glu:
0
0
8
0
16
0
8
8
39
8
0
0
0
24
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
8
% F
% Gly:
0
0
0
0
0
8
0
0
0
0
0
0
0
47
0
% G
% His:
0
8
0
8
31
0
54
0
8
0
0
16
0
0
0
% H
% Ile:
0
16
0
0
0
0
0
0
0
0
0
8
0
0
0
% I
% Lys:
8
8
8
0
8
0
0
0
0
8
16
0
0
0
0
% K
% Leu:
0
0
77
0
0
54
0
0
39
0
47
54
0
8
77
% L
% Met:
0
0
0
0
0
16
0
8
0
8
0
0
0
0
16
% M
% Asn:
0
39
8
16
0
0
31
0
0
0
0
0
16
0
0
% N
% Pro:
0
0
0
0
16
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
8
0
0
39
0
0
47
0
0
% Q
% Arg:
0
0
0
0
0
24
0
0
8
31
16
0
24
0
0
% R
% Ser:
31
8
0
8
8
0
0
47
0
0
0
16
0
0
0
% S
% Thr:
0
16
0
54
8
0
0
8
0
0
0
0
0
16
0
% T
% Val:
8
0
0
8
0
0
0
8
0
0
16
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _