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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KLHL28
All Species:
24.55
Human Site:
S398
Identified Species:
45
UniProt:
Q9NXS3
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NXS3
NP_060128.2
571
64192
S398
L
G
G
Y
D
G
Q
S
Y
L
Q
S
V
E
K
Chimpanzee
Pan troglodytes
XP_001149345
684
76181
R507
S
C
L
N
I
V
E
R
Y
D
P
K
E
N
K
Rhesus Macaque
Macaca mulatta
XP_001095031
571
64184
S398
L
G
G
Y
D
G
Q
S
Y
L
Q
S
V
E
K
Dog
Lupus familis
XP_547790
571
64226
S398
L
G
G
Y
D
G
Q
S
Y
L
Q
S
V
E
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9CR40
571
64107
S398
L
G
G
Y
D
G
Q
S
Y
L
Q
S
V
E
K
Rat
Rattus norvegicus
Q8K430
640
69714
Y454
C
L
N
S
A
E
R
Y
D
P
L
T
G
T
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513616
571
64248
S398
L
G
G
Y
D
G
Q
S
Y
L
Q
S
V
E
K
Chicken
Gallus gallus
Q5ZI33
586
66177
T407
F
E
C
Y
D
T
R
T
E
S
W
H
T
K
P
Frog
Xenopus laevis
Q6NRH0
564
63190
M392
G
S
R
R
H
T
S
M
E
R
Y
D
P
N
I
Zebra Danio
Brachydanio rerio
Q5U374
564
62914
M392
G
S
R
R
H
T
S
M
E
R
Y
D
P
N
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VUU5
623
68905
R436
Q
C
L
N
H
V
E
R
Y
D
P
K
E
N
K
Honey Bee
Apis mellifera
XP_397065
620
68991
R443
Q
C
L
N
H
V
E
R
Y
D
P
K
E
N
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780225
597
66997
S424
L
G
G
Y
N
G
E
S
Y
M
K
N
V
E
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
36.9
99.4
99.1
N.A.
97
38.4
N.A.
93.1
32.7
38.7
38.3
N.A.
40.1
40
N.A.
46.2
Protein Similarity:
100
53
99.4
99.6
N.A.
99.1
53.4
N.A.
96.6
50.5
56.7
57
N.A.
56.1
56.2
N.A.
65.1
P-Site Identity:
100
13.3
100
100
N.A.
100
0
N.A.
100
13.3
0
0
N.A.
13.3
13.3
N.A.
60
P-Site Similarity:
100
20
100
100
N.A.
100
13.3
N.A.
100
33.3
0
0
N.A.
20
20
N.A.
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
8
24
8
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
47
0
0
0
8
24
0
16
0
0
0
% D
% Glu:
0
8
0
0
0
8
31
0
24
0
0
0
24
47
0
% E
% Phe:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
16
47
47
0
0
47
0
0
0
0
0
0
8
0
0
% G
% His:
0
0
0
0
31
0
0
0
0
0
0
8
0
0
0
% H
% Ile:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
16
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
8
24
0
8
62
% K
% Leu:
47
8
24
0
0
0
0
0
0
39
8
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
16
0
8
0
0
0
0
0
% M
% Asn:
0
0
8
24
8
0
0
0
0
0
0
8
0
39
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
8
24
0
16
0
8
% P
% Gln:
16
0
0
0
0
0
39
0
0
0
39
0
0
0
0
% Q
% Arg:
0
0
16
16
0
0
16
24
0
16
0
0
0
0
0
% R
% Ser:
8
16
0
8
0
0
16
47
0
8
0
39
0
0
0
% S
% Thr:
0
0
0
0
0
24
0
8
0
0
0
8
8
8
0
% T
% Val:
0
0
0
0
0
24
0
0
0
0
0
0
47
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
8
% W
% Tyr:
0
0
0
54
0
0
0
8
70
0
16
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _