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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KLHL28
All Species:
32.12
Human Site:
S538
Identified Species:
58.89
UniProt:
Q9NXS3
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NXS3
NP_060128.2
571
64192
S538
V
G
G
H
S
G
S
S
Y
L
N
T
V
Q
K
Chimpanzee
Pan troglodytes
XP_001149345
684
76181
T641
V
G
G
F
D
G
T
T
Y
L
K
T
I
E
V
Rhesus Macaque
Macaca mulatta
XP_001095031
571
64184
S538
V
G
G
H
S
G
S
S
Y
L
N
T
V
Q
K
Dog
Lupus familis
XP_547790
571
64226
S538
V
G
G
H
S
G
S
S
Y
L
N
T
V
Q
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9CR40
571
64107
S538
V
G
G
H
S
G
S
S
Y
L
N
T
V
Q
K
Rat
Rattus norvegicus
Q8K430
640
69714
S587
V
G
G
N
D
G
S
S
S
L
N
S
I
E
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513616
571
64248
S538
V
G
G
H
S
G
S
S
Y
L
N
T
V
Q
K
Chicken
Gallus gallus
Q5ZI33
586
66177
G540
L
A
G
F
Q
G
V
G
R
L
G
H
I
L
E
Frog
Xenopus laevis
Q6NRH0
564
63190
S528
I
A
G
Y
D
G
N
S
L
L
N
S
V
E
C
Zebra Danio
Brachydanio rerio
Q5U374
564
62914
S528
I
A
G
Y
D
G
N
S
L
L
S
S
I
E
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VUU5
623
68905
A570
V
G
G
F
D
G
S
A
Y
L
K
T
I
E
V
Honey Bee
Apis mellifera
XP_397065
620
68991
A577
V
G
G
F
D
G
T
A
Y
L
K
T
I
E
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780225
597
66997
A564
A
G
G
H
S
G
A
A
Y
L
D
R
V
E
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
36.9
99.4
99.1
N.A.
97
38.4
N.A.
93.1
32.7
38.7
38.3
N.A.
40.1
40
N.A.
46.2
Protein Similarity:
100
53
99.4
99.6
N.A.
99.1
53.4
N.A.
96.6
50.5
56.7
57
N.A.
56.1
56.2
N.A.
65.1
P-Site Identity:
100
46.6
100
100
N.A.
100
60
N.A.
100
20
40
26.6
N.A.
53.3
46.6
N.A.
60
P-Site Similarity:
100
73.3
100
100
N.A.
100
86.6
N.A.
100
40
73.3
73.3
N.A.
73.3
73.3
N.A.
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
24
0
0
0
0
8
24
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
16
% C
% Asp:
0
0
0
0
47
0
0
0
0
0
8
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
54
8
% E
% Phe:
0
0
0
31
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
77
100
0
0
100
0
8
0
0
8
0
0
0
0
% G
% His:
0
0
0
47
0
0
0
0
0
0
0
8
0
0
0
% H
% Ile:
16
0
0
0
0
0
0
0
0
0
0
0
47
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
24
0
0
0
54
% K
% Leu:
8
0
0
0
0
0
0
0
16
100
0
0
0
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
8
0
0
16
0
0
0
54
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
8
0
0
0
0
0
0
0
0
39
0
% Q
% Arg:
0
0
0
0
0
0
0
0
8
0
0
8
0
0
0
% R
% Ser:
0
0
0
0
47
0
54
62
8
0
8
24
0
0
0
% S
% Thr:
0
0
0
0
0
0
16
8
0
0
0
62
0
0
0
% T
% Val:
70
0
0
0
0
0
8
0
0
0
0
0
54
0
24
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
16
0
0
0
0
70
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _