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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KLHL28
All Species:
27.27
Human Site:
Y216
Identified Species:
50
UniProt:
Q9NXS3
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NXS3
NP_060128.2
571
64192
Y216
D
V
Q
E
R
Q
K
Y
L
A
Q
L
L
N
S
Chimpanzee
Pan troglodytes
XP_001149345
684
76181
Q324
S
I
Q
E
R
R
P
Q
L
P
Q
V
L
Q
H
Rhesus Macaque
Macaca mulatta
XP_001095031
571
64184
Y216
D
V
Q
E
R
Q
K
Y
L
A
Q
L
L
N
S
Dog
Lupus familis
XP_547790
571
64226
Y216
D
V
Q
E
R
Q
K
Y
L
A
Q
L
L
N
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9CR40
571
64107
Y216
D
V
Q
E
R
Q
K
Y
L
A
Q
L
L
N
S
Rat
Rattus norvegicus
Q8K430
640
69714
H271
D
V
D
T
R
R
Q
H
V
P
R
L
M
K
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513616
571
64248
Y216
D
V
Q
E
R
Q
K
Y
L
G
Q
L
L
H
C
Chicken
Gallus gallus
Q5ZI33
586
66177
Y225
D
E
P
N
R
Q
P
Y
M
V
D
I
L
A
K
Frog
Xenopus laevis
Q6NRH0
564
63190
S210
N
R
H
E
R
E
K
S
L
P
Q
L
L
Q
Y
Zebra Danio
Brachydanio rerio
Q5U374
564
62914
Y210
N
R
K
E
R
E
P
Y
L
P
D
L
L
E
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VUU5
623
68905
H253
N
V
A
E
R
R
Q
H
L
A
Q
V
L
Q
H
Honey Bee
Apis mellifera
XP_397065
620
68991
H260
N
V
T
E
R
R
Q
H
L
A
Q
V
L
Q
H
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780225
597
66997
Y240
D
P
N
R
R
Q
C
Y
L
G
R
A
L
Q
C
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
36.9
99.4
99.1
N.A.
97
38.4
N.A.
93.1
32.7
38.7
38.3
N.A.
40.1
40
N.A.
46.2
Protein Similarity:
100
53
99.4
99.6
N.A.
99.1
53.4
N.A.
96.6
50.5
56.7
57
N.A.
56.1
56.2
N.A.
65.1
P-Site Identity:
100
40
100
100
N.A.
100
26.6
N.A.
80
33.3
46.6
40
N.A.
46.6
46.6
N.A.
40
P-Site Similarity:
100
60
100
100
N.A.
100
66.6
N.A.
86.6
46.6
60
60
N.A.
80
80
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
0
0
0
0
47
0
8
0
8
0
% A
% Cys:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
24
% C
% Asp:
62
0
8
0
0
0
0
0
0
0
16
0
0
0
0
% D
% Glu:
0
8
0
77
0
16
0
0
0
0
0
0
0
8
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
16
0
0
0
0
0
% G
% His:
0
0
8
0
0
0
0
24
0
0
0
0
0
8
24
% H
% Ile:
0
8
0
0
0
0
0
0
0
0
0
8
0
0
0
% I
% Lys:
0
0
8
0
0
0
47
0
0
0
0
0
0
8
8
% K
% Leu:
0
0
0
0
0
0
0
0
85
0
0
62
93
0
0
% L
% Met:
0
0
0
0
0
0
0
0
8
0
0
0
8
0
0
% M
% Asn:
31
0
8
8
0
0
0
0
0
0
0
0
0
31
0
% N
% Pro:
0
8
8
0
0
0
24
0
0
31
0
0
0
0
0
% P
% Gln:
0
0
47
0
0
54
24
8
0
0
70
0
0
39
0
% Q
% Arg:
0
16
0
8
100
31
0
0
0
0
16
0
0
0
0
% R
% Ser:
8
0
0
0
0
0
0
8
0
0
0
0
0
0
31
% S
% Thr:
0
0
8
8
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
62
0
0
0
0
0
0
8
8
0
24
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
62
0
0
0
0
0
0
16
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _