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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KLHL28
All Species:
30.61
Human Site:
Y304
Identified Species:
56.11
UniProt:
Q9NXS3
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NXS3
NP_060128.2
571
64192
Y304
C
L
D
S
V
E
M
Y
F
P
Q
N
D
S
W
Chimpanzee
Pan troglodytes
XP_001149345
684
76181
Y413
A
I
S
S
V
E
R
Y
D
P
Q
T
N
E
W
Rhesus Macaque
Macaca mulatta
XP_001095031
571
64184
Y304
C
L
D
S
V
E
M
Y
F
P
Q
N
D
S
W
Dog
Lupus familis
XP_547790
571
64226
Y304
C
L
D
S
V
E
M
Y
F
P
Q
N
D
S
W
Cat
Felis silvestris
Mouse
Mus musculus
Q9CR40
571
64107
Y304
C
L
D
S
V
E
M
Y
F
P
Q
N
D
S
W
Rat
Rattus norvegicus
Q8K430
640
69714
Y360
I
H
G
D
C
E
A
Y
D
T
R
T
D
R
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513616
571
64248
Y304
C
L
E
S
V
E
M
Y
F
P
Q
N
D
S
W
Chicken
Gallus gallus
Q5ZI33
586
66177
D313
C
R
Y
F
N
P
K
D
Y
S
W
T
D
I
R
Frog
Xenopus laevis
Q6NRH0
564
63190
Y298
P
I
D
I
V
E
K
Y
D
P
K
T
Q
E
W
Zebra Danio
Brachydanio rerio
Q5U374
564
62914
Y298
P
I
D
I
V
E
K
Y
D
P
K
T
R
E
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VUU5
623
68905
F342
A
I
A
S
V
E
R
F
D
P
Q
T
N
D
W
Honey Bee
Apis mellifera
XP_397065
620
68991
F349
A
I
A
S
V
E
R
F
D
P
N
T
A
D
W
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780225
597
66997
Y330
T
L
D
S
V
E
V
Y
R
S
E
T
D
S
W
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
36.9
99.4
99.1
N.A.
97
38.4
N.A.
93.1
32.7
38.7
38.3
N.A.
40.1
40
N.A.
46.2
Protein Similarity:
100
53
99.4
99.6
N.A.
99.1
53.4
N.A.
96.6
50.5
56.7
57
N.A.
56.1
56.2
N.A.
65.1
P-Site Identity:
100
46.6
100
100
N.A.
100
26.6
N.A.
93.3
13.3
40
40
N.A.
40
33.3
N.A.
60
P-Site Similarity:
100
60
100
100
N.A.
100
33.3
N.A.
100
20
53.3
53.3
N.A.
60
46.6
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
24
0
16
0
0
0
8
0
0
0
0
0
8
0
0
% A
% Cys:
47
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
54
8
0
0
0
8
47
0
0
0
62
16
0
% D
% Glu:
0
0
8
0
0
93
0
0
0
0
8
0
0
24
0
% E
% Phe:
0
0
0
8
0
0
0
16
39
0
0
0
0
0
0
% F
% Gly:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
39
0
16
0
0
0
0
0
0
0
0
0
8
0
% I
% Lys:
0
0
0
0
0
0
24
0
0
0
16
0
0
0
0
% K
% Leu:
0
47
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
39
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
8
0
0
0
0
0
8
39
16
0
0
% N
% Pro:
16
0
0
0
0
8
0
0
0
77
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
54
0
8
0
0
% Q
% Arg:
0
8
0
0
0
0
24
0
8
0
8
0
8
8
8
% R
% Ser:
0
0
8
70
0
0
0
0
0
16
0
0
0
47
0
% S
% Thr:
8
0
0
0
0
0
0
0
0
8
0
62
0
0
0
% T
% Val:
0
0
0
0
85
0
8
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
93
% W
% Tyr:
0
0
8
0
0
0
0
77
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _