KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KLHL28
All Species:
22.12
Human Site:
Y452
Identified Species:
40.56
UniProt:
Q9NXS3
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NXS3
NP_060128.2
571
64192
Y452
H
M
N
S
V
E
R
Y
D
P
S
K
D
S
W
Chimpanzee
Pan troglodytes
XP_001149345
684
76181
R561
R
Y
N
P
Q
E
N
R
W
H
T
I
A
P
M
Rhesus Macaque
Macaca mulatta
XP_001095031
571
64184
Y452
H
M
N
S
V
E
R
Y
D
P
S
K
D
S
W
Dog
Lupus familis
XP_547790
571
64226
Y452
H
M
N
S
V
E
R
Y
D
P
S
K
D
S
W
Cat
Felis silvestris
Mouse
Mus musculus
Q9CR40
571
64107
Y452
H
M
N
S
V
E
R
Y
D
P
S
K
D
S
W
Rat
Rattus norvegicus
Q8K430
640
69714
W508
Y
E
P
Q
V
N
S
W
T
P
V
A
S
M
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513616
571
64248
Y452
H
M
N
S
V
E
R
Y
D
P
S
K
D
S
W
Chicken
Gallus gallus
Q5ZI33
586
66177
W461
Y
D
P
A
T
E
T
W
T
E
L
C
P
M
I
Frog
Xenopus laevis
Q6NRH0
564
63190
T446
V
E
R
Y
D
P
H
T
G
H
W
S
H
V
T
Zebra Danio
Brachydanio rerio
Q5U374
564
62914
T446
V
E
R
Y
D
P
H
T
G
H
W
T
S
V
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VUU5
623
68905
K490
R
Y
D
P
R
H
N
K
W
V
A
V
S
P
M
Honey Bee
Apis mellifera
XP_397065
620
68991
K497
R
Y
D
P
R
Q
N
K
W
S
Q
V
S
P
M
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780225
597
66997
Y478
Y
L
N
S
M
E
R
Y
D
P
D
K
D
F
W
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
36.9
99.4
99.1
N.A.
97
38.4
N.A.
93.1
32.7
38.7
38.3
N.A.
40.1
40
N.A.
46.2
Protein Similarity:
100
53
99.4
99.6
N.A.
99.1
53.4
N.A.
96.6
50.5
56.7
57
N.A.
56.1
56.2
N.A.
65.1
P-Site Identity:
100
13.3
100
100
N.A.
100
13.3
N.A.
100
6.6
0
0
N.A.
0
0
N.A.
66.6
P-Site Similarity:
100
20
100
100
N.A.
100
26.6
N.A.
100
26.6
0
0
N.A.
13.3
13.3
N.A.
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
0
0
0
0
0
8
8
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% C
% Asp:
0
8
16
0
16
0
0
0
47
0
8
0
47
0
0
% D
% Glu:
0
24
0
0
0
62
0
0
0
8
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% F
% Gly:
0
0
0
0
0
0
0
0
16
0
0
0
0
0
0
% G
% His:
39
0
0
0
0
8
16
0
0
24
0
0
8
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
8
% I
% Lys:
0
0
0
0
0
0
0
16
0
0
0
47
0
0
0
% K
% Leu:
0
8
0
0
0
0
0
0
0
0
8
0
0
0
8
% L
% Met:
0
39
0
0
8
0
0
0
0
0
0
0
0
16
24
% M
% Asn:
0
0
54
0
0
8
24
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
16
24
0
16
0
0
0
54
0
0
8
24
0
% P
% Gln:
0
0
0
8
8
8
0
0
0
0
8
0
0
0
0
% Q
% Arg:
24
0
16
0
16
0
47
8
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
47
0
0
8
0
0
8
39
8
31
39
0
% S
% Thr:
0
0
0
0
8
0
8
16
16
0
8
8
0
0
16
% T
% Val:
16
0
0
0
47
0
0
0
0
8
8
16
0
16
0
% V
% Trp:
0
0
0
0
0
0
0
16
24
0
16
0
0
0
47
% W
% Tyr:
24
24
0
16
0
0
0
47
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _