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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDKN2AIP
All Species:
7.58
Human Site:
S376
Identified Species:
20.83
UniProt:
Q9NXV6
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NXV6
NP_060102.1
579
61054
S376
L
L
A
S
K
S
S
S
Q
T
S
G
S
L
V
Chimpanzee
Pan troglodytes
XP_001160971
242
26083
D62
A
S
T
D
E
A
A
D
A
E
S
G
T
R
N
Rhesus Macaque
Macaca mulatta
XP_001093046
580
61058
S377
L
L
A
S
K
S
S
S
Q
T
S
G
S
L
V
Dog
Lupus familis
XP_849962
578
61041
S372
A
S
L
L
A
S
K
S
S
S
Q
T
S
G
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8BI72
563
59726
G369
S
L
L
A
T
K
S
G
A
S
L
G
S
V
S
Rat
Rattus norvegicus
Q5U2X0
570
60725
S369
S
K
S
S
S
Q
S
S
G
S
V
A
S
K
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001232632
512
51765
A332
Q
G
P
S
R
S
G
A
Q
A
A
K
S
S
Q
Frog
Xenopus laevis
Q7ZXV6
398
44771
K218
H
G
A
T
Q
G
R
K
S
H
S
D
I
R
H
Zebra Danio
Brachydanio rerio
NP_001006085
312
34921
K132
D
A
D
Y
Q
G
K
K
N
K
P
N
E
P
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
41.2
97.9
91.8
N.A.
85.3
87.9
N.A.
N.A.
38.5
43.1
30.3
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
41.4
98.4
95.8
N.A.
91.1
93.2
N.A.
N.A.
55.4
55
40.4
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
13.3
100
20
N.A.
26.6
26.6
N.A.
N.A.
26.6
13.3
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
40
100
26.6
N.A.
46.6
40
N.A.
N.A.
46.6
26.6
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
23
12
34
12
12
12
12
12
23
12
12
12
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
12
0
12
12
0
0
0
12
0
0
0
12
0
0
12
% D
% Glu:
0
0
0
0
12
0
0
0
0
12
0
0
12
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
23
0
0
0
23
12
12
12
0
0
45
0
12
0
% G
% His:
12
0
0
0
0
0
0
0
0
12
0
0
0
0
12
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% I
% Lys:
0
12
0
0
23
12
23
23
0
12
0
12
0
12
0
% K
% Leu:
23
34
23
12
0
0
0
0
0
0
12
0
0
23
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
12
0
0
12
0
0
12
% N
% Pro:
0
0
12
0
0
0
0
0
0
0
12
0
0
12
0
% P
% Gln:
12
0
0
0
23
12
0
0
34
0
12
0
0
0
12
% Q
% Arg:
0
0
0
0
12
0
12
0
0
0
0
0
0
23
0
% R
% Ser:
23
23
12
45
12
45
45
45
23
34
45
0
67
12
34
% S
% Thr:
0
0
12
12
12
0
0
0
0
23
0
12
12
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
12
0
0
12
23
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _