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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDKN2AIP
All Species:
4.55
Human Site:
Y443
Identified Species:
12.5
UniProt:
Q9NXV6
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NXV6
NP_060102.1
579
61054
Y443
Q
P
F
F
N
R
L
Y
K
T
V
A
W
K
L
Chimpanzee
Pan troglodytes
XP_001160971
242
26083
G129
V
A
K
V
K
K
R
G
I
S
S
S
N
E
G
Rhesus Macaque
Macaca mulatta
XP_001093046
580
61058
Y444
Q
P
F
F
N
R
L
Y
K
T
V
A
W
K
L
Dog
Lupus familis
XP_849962
578
61041
N439
K
Q
K
Q
P
F
F
N
R
L
Y
K
T
V
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8BI72
563
59726
A436
T
V
A
W
K
L
V
A
V
G
G
F
S
P
T
Rat
Rattus norvegicus
Q5U2X0
570
60725
T436
F
F
N
R
L
Y
K
T
V
A
W
K
L
V
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001232632
512
51765
L399
N
V
N
H
A
E
L
L
N
S
S
I
Q
S
V
Frog
Xenopus laevis
Q7ZXV6
398
44771
L285
N
L
N
H
E
E
L
L
N
T
C
I
E
S
L
Zebra Danio
Brachydanio rerio
NP_001006085
312
34921
R199
L
E
H
F
E
I
L
R
S
C
V
E
S
C
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
41.2
97.9
91.8
N.A.
85.3
87.9
N.A.
N.A.
38.5
43.1
30.3
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
41.4
98.4
95.8
N.A.
91.1
93.2
N.A.
N.A.
55.4
55
40.4
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
0
100
0
N.A.
0
0
N.A.
N.A.
6.6
20
20
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
26.6
100
13.3
N.A.
13.3
0
N.A.
N.A.
20
20
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
12
12
0
12
0
0
12
0
12
0
23
0
0
23
% A
% Cys:
0
0
0
0
0
0
0
0
0
12
12
0
0
12
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
12
0
0
23
23
0
0
0
0
0
12
12
12
0
% E
% Phe:
12
12
23
34
0
12
12
0
0
0
0
12
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
12
0
12
12
0
0
0
12
% G
% His:
0
0
12
23
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
12
0
0
12
0
0
23
0
0
0
% I
% Lys:
12
0
23
0
23
12
12
0
23
0
0
23
0
23
12
% K
% Leu:
12
12
0
0
12
12
56
23
0
12
0
0
12
0
34
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
23
0
34
0
23
0
0
12
23
0
0
0
12
0
0
% N
% Pro:
0
23
0
0
12
0
0
0
0
0
0
0
0
12
0
% P
% Gln:
23
12
0
12
0
0
0
0
0
0
0
0
12
0
0
% Q
% Arg:
0
0
0
12
0
23
12
12
12
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
12
23
23
12
23
23
0
% S
% Thr:
12
0
0
0
0
0
0
12
0
34
0
0
12
0
12
% T
% Val:
12
23
0
12
0
0
12
0
23
0
34
0
0
23
12
% V
% Trp:
0
0
0
12
0
0
0
0
0
0
12
0
23
0
0
% W
% Tyr:
0
0
0
0
0
12
0
23
0
0
12
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _