KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NSMCE4A
All Species:
20.91
Human Site:
S258
Identified Species:
51.11
UniProt:
Q9NXX6
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NXX6
NP_060085.1
385
44301
S258
Q
L
R
R
M
E
E
S
H
Q
E
A
T
E
K
Chimpanzee
Pan troglodytes
XP_001157827
385
44267
S258
Q
L
R
R
M
E
E
S
H
Q
E
A
T
E
K
Rhesus Macaque
Macaca mulatta
XP_001101717
385
44167
S258
Q
L
R
R
M
E
E
S
H
Q
E
A
T
E
K
Dog
Lupus familis
XP_535041
525
58515
S398
Q
L
S
E
M
E
E
S
H
Q
E
A
T
E
K
Cat
Felis silvestris
Mouse
Mus musculus
Q3V124
375
43289
A255
L
R
R
L
D
V
H
A
N
Q
E
T
T
E
K
Rat
Rattus norvegicus
Q4V8G2
387
44766
A267
L
R
K
L
D
V
H
A
N
Q
E
T
T
E
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515150
504
55597
S375
T
K
E
K
M
E
E
S
H
Q
E
A
T
E
K
Chicken
Gallus gallus
XP_421797
395
44643
S269
Q
L
K
K
M
E
E
S
H
Q
E
A
T
A
K
Frog
Xenopus laevis
NP_001121344
334
38061
Q217
K
K
M
E
E
S
H
Q
E
A
T
E
K
E
V
Zebra Danio
Brachydanio rerio
NP_001018359
346
38956
M228
M
P
T
Q
L
K
K
M
E
E
S
H
Q
E
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.6
97.6
57.3
N.A.
44.9
47.5
N.A.
39.8
51.1
48.3
44.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
98.9
98.9
63.6
N.A.
62
62.5
N.A.
51.7
66.5
63.3
60
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
86.6
N.A.
40
33.3
N.A.
73.3
80
6.6
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
86.6
N.A.
53.3
53.3
N.A.
80
93.3
13.3
40
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
20
0
10
0
60
0
10
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
20
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
10
20
10
60
60
0
20
10
80
10
0
90
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
30
0
60
0
0
10
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
10
20
20
20
0
10
10
0
0
0
0
0
10
0
80
% K
% Leu:
20
50
0
20
10
0
0
0
0
0
0
0
0
0
0
% L
% Met:
10
0
10
0
60
0
0
10
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
20
0
0
0
0
0
0
% N
% Pro:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
50
0
0
10
0
0
0
10
0
80
0
0
10
0
0
% Q
% Arg:
0
20
40
30
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
10
0
0
10
0
60
0
0
10
0
0
0
0
% S
% Thr:
10
0
10
0
0
0
0
0
0
0
10
20
80
0
0
% T
% Val:
0
0
0
0
0
20
0
0
0
0
0
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _