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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDX43
All Species:
17.58
Human Site:
S346
Identified Species:
32.22
UniProt:
Q9NXZ2
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NXZ2
NP_061135.2
648
72844
S346
Y
S
Y
K
G
L
R
S
V
C
V
Y
G
G
G
Chimpanzee
Pan troglodytes
XP_518584
648
72811
S346
Y
S
Y
K
G
L
R
S
V
C
V
Y
G
G
G
Rhesus Macaque
Macaca mulatta
XP_001112413
648
73197
S346
Y
S
Y
K
G
L
R
S
V
C
V
Y
G
G
G
Dog
Lupus familis
XP_853740
646
73189
S344
Y
S
Y
K
G
L
K
S
V
C
I
Y
G
G
G
Cat
Felis silvestris
Mouse
Mus musculus
XP_001480973
646
72253
S344
Y
S
Y
G
D
L
K
S
V
C
V
Y
G
G
G
Rat
Rattus norvegicus
XP_001060057
620
69575
G325
S
V
C
V
Y
G
G
G
D
R
D
G
Q
I
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_426195
445
49951
A192
L
A
P
T
R
E
L
A
L
Q
V
E
A
E
C
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P19109
719
78529
N385
G
S
S
S
Y
V
R
N
T
C
V
F
G
G
A
Honey Bee
Apis mellifera
XP_394925
593
68127
R339
L
V
L
D
E
A
D
R
M
L
D
M
G
F
E
Nematode Worm
Caenorhab. elegans
NP_496973
504
56752
M251
E
A
D
R
M
L
D
M
G
F
E
V
A
I
R
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8W4R3
591
64603
P331
M
L
D
M
G
F
E
P
Q
I
R
K
I
V
S
Baker's Yeast
Sacchar. cerevisiae
P24783
546
60981
Q293
D
Q
I
R
P
D
R
Q
T
L
M
W
S
A
T
Red Bread Mold
Neurospora crassa
Q7SBC6
562
60181
P309
K
I
I
G
Q
I
R
P
D
R
Q
T
L
M
W
Conservation
Percent
Protein Identity:
100
99
96.7
75.9
N.A.
76.8
74.5
N.A.
N.A.
47.9
N.A.
N.A.
N.A.
29.7
45.3
36.5
N.A.
Protein Similarity:
100
99.6
97.9
87.1
N.A.
86.1
83
N.A.
N.A.
57.4
N.A.
N.A.
N.A.
47.9
62.9
51.2
N.A.
P-Site Identity:
100
100
100
86.6
N.A.
80
0
N.A.
N.A.
6.6
N.A.
N.A.
N.A.
40
6.6
6.6
N.A.
P-Site Similarity:
100
100
100
100
N.A.
86.6
0
N.A.
N.A.
26.6
N.A.
N.A.
N.A.
60
13.3
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
36.2
36.1
34.2
Protein Similarity:
N.A.
N.A.
N.A.
53.7
54.1
51
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
26.6
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
16
0
0
0
8
0
8
0
0
0
0
16
8
8
% A
% Cys:
0
0
8
0
0
0
0
0
0
47
0
0
0
0
8
% C
% Asp:
8
0
16
8
8
8
16
0
16
0
16
0
0
0
0
% D
% Glu:
8
0
0
0
8
8
8
0
0
0
8
8
0
8
8
% E
% Phe:
0
0
0
0
0
8
0
0
0
8
0
8
0
8
0
% F
% Gly:
8
0
0
16
39
8
8
8
8
0
0
8
54
47
39
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
16
0
0
8
0
0
0
8
8
0
8
16
0
% I
% Lys:
8
0
0
31
0
0
16
0
0
0
0
8
0
0
0
% K
% Leu:
16
8
8
0
0
47
8
0
8
16
0
0
8
0
0
% L
% Met:
8
0
0
8
8
0
0
8
8
0
8
8
0
8
0
% M
% Asn:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% N
% Pro:
0
0
8
0
8
0
0
16
0
0
0
0
0
0
0
% P
% Gln:
0
8
0
0
8
0
0
8
8
8
8
0
8
0
8
% Q
% Arg:
0
0
0
16
8
0
47
8
0
16
8
0
0
0
8
% R
% Ser:
8
47
8
8
0
0
0
39
0
0
0
0
8
0
8
% S
% Thr:
0
0
0
8
0
0
0
0
16
0
0
8
0
0
8
% T
% Val:
0
16
0
8
0
8
0
0
39
0
47
8
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
8
% W
% Tyr:
39
0
39
0
16
0
0
0
0
0
0
39
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _